【生薬学分野2016年の業績】


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2015年業績
2017年業績

(原報)

Shengli Gao, Hirotaka Kushida, Toshiaki Makino
Ginsenosides, ingredients of the root of Panax ginseng, are not substrates but inhibitors of sodium-glucose transporter 1
J. Nat. Med. (in press)(2016)

Tsukasa Fueki, Koki Chiba, Toshiaki Makino, Takanori Matsuoka, Tadaaki Satou, Kazuo Koike, Koichiro Tanaka, Megumi Sumino, Takao Namiki
Quick and easy preparation method for Kampo formula decoctions (part 4): IPCD method for rhubarb and aconite root
Traditional & Kampo Medicine 3(2): 170-173 (2016)

Kan'ichiro Ishiuchi, Wen-Ping Jiang, Yukio Fujiwara, Jin-Bin Wu, Susumu Kitanaka
Serralongamines B-D, three new Lycopodium alkaloids from Lycopodium serratum var. longipetiolatum, and their inhibitory effects on foam cell formation in macrophages
Bioorg. Med. Chem. Lett. 26(11): 2636-2640 (2016)

Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Yuka Kitao, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain
J. Ethnopharmacol. 186: 44-52 (2016)

Tsukasa Fueki, Megumi Sumino, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Koichiro Tanaka, Takao Namiki
Quick and easy preparation method for decoctions of kampo formula (part 3): Extraction efficiency of the IPCD method for volatile compounds
Traditional & Kampo Medicine in press (2016)

Toru Konishi, Masaaki Minami, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Antibacterial activity of Shin'iseihaito (Xin Yi Qing Fei Tang) against Streptococcus pneumoniae
Pharmacogn. J. 8(1): 20-23 (2016)

(総説・著書・総合論文など)

三巻祥浩,小林義典,牧野利明
生薬学担当教員による漢方教育に対する取り組み
生薬学雑誌 136(3): 397-398 (2016)

牧野利明
漢方の国際化時代における漢方教育のあり方
生薬学雑誌 136(3): 411-415 (2016)

(学会発表)

[Symposium]
Toshiaki Makino
Concept on active ingredients of crude drugs used in Kampo Medicine
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Toshiaki Makino
Anti-allergic effect of Shoseiryuto (小青竜湯) and Byakkokankeishito (白虎加桂枝湯) and the roles of each components – the roles of peony root (芍薬) and gypsum (石膏) in these formulas
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

[薬剤師向け漢方講座]
牧野利明
漢方エキス製剤の特徴を知り、服薬指導に生かす
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

[口頭]
○Ke Ye, Kan’ichiro Ishiuchi, Tomoaki Ishida, Yuki Kishida, Keisuke Hagihara, Tomonori Abe, Takeshi Nikawa, Hidetoshi Hayashi, Toshiaki Makino
In vitro preventive effect of the extract of goshajinkigan (牛車腎気丸) on muscle atrophy and its active constituents
The 7th Nagoya/Nanjing/Shenyang Symposium of Pharmaceutical Sciences, 2016. 9. 24-25, Nagoya, Japan

[ポスター]
○Fuzi Zhang, Tomoyasu Murakami, Kan’ichiro Ishiuchi, Akinori Sugiyama, Masahiro Ohsawa, Toshiaki Makino
Comparison of the capitulum from Chrysanthemum morifolium and C. indicum about the agonistic activity on peroxisome proliferator-activated receptor-γ and their active constituents
The 7th Nagoya/Nanjing/Shenyang Symposium of Pharmaceutical Sciences, 2016. 9. 24-25, Nagoya, Japan

○Shengli Gao, Toshiaki Makino
Ginsenosides, the ingredients of root of Panax ginseng, are not absorbed via sodium-glucose transporter 1 (SGLT1) but inhibit it
The 7th Nagoya/Nanjing/Shenyang Symposium of Pharmaceutical Sciences, 2016. 9. 24-25, Nagoya, Japan

○Chuan Ting Tian, Tsuyoshi Ohkita, Kan’ichiro Ishiuchi, Osamu Morinaga, Toshiaki Makino
Pathogenic agents of licorice-induced pseudoaldosteronism
The 7th Nagoya/Nanjing/Shenyang Symposium of Pharmaceutical Sciences, 2016. 9. 24-25, Nagoya, Japan

○小西徹、南正明、牧野利明
メチシリン耐性黄色ブドウ球菌に対する辛夷清肺湯及びその構成生薬の抗菌活性の検討
日本生薬学会第63回年会、2016年9月24日 (富山) ;1P-06

中山和香、○石内勘一郎、Orawan Monthakantirat、藤川和美、Santi Watthana、北中進、牧野利明
ヒカゲノカズラ科植物由来新規lycopodane型アルカロイドの構造
日本生薬学会第63回年会、2016年9月24日 (富山) ;2P-50

Masaaki Minami, Toru Konishi, Toshiaki Makino
Effect of Yin Qiao San against Streptococcus pneumoniae murine model by microarray analysis
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Ke Ye, Tomoaki Ishida, Yuki Kishida, Keisuke Hagihara, Tomonori Abe, Takeshi Nikawa, Hidetoshi Hayashi, Toshiaki Makino
In vitro preventive effect of the extract of goshajinkigan (牛車腎気丸) on muscle atrophy and its active constituents
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Tomoaki Ishida, Yuki Kishida, Keisuke Hagihara, Toshiaki Makino
Effect of goshajinkigan (牛車腎気丸) on muscle atrophy in senescence-accelerated mice and its active constituents
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
Processed aconite root (附子) and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Fuzi Zhang, Kan'ichiro Ishiuchi, Akinori Sugiyama, Masahiro Ohsawa, Toshiaki Makino
Comparison of Chrysanthemi Flos (菊花) derived from Chrysanthemum morifolium and C. indicum about the agonistic activity on PPAR-gamma and their active ingredients
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Rie Iijima, Kan’ichiro Ishiuchi, Toshiaki Makino
Screening of crude drugs used in Japanese traditional Kampo medicine that have inhibitory effect of organic anion transporting peptide (OATP)-2B1
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Misato Ota, Masayuki Mikage, Toshiaki Makino, Shao-Qing Cai
Studies on processed licorice (1) – Herbological and chemical studies of roasted licorice (炙甘草) and honey-roasted licorice (蜜炙甘草)
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Yasutaka Nagachi, Misato Ota, Yoshiaki Tabuchi, Shao-Qing Cai, Toshiaki Makino
Studies on processed licorice (2) - Comparison of the immunostimulatory effects among licorice (甘草) samples with or without heat-processing and pre-treatment with honey in cultured intestinal epithelial cells
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

Tsukasa Fueki, Toshiaki Makino, Megumi Sumino, Takanori Matsuoka, Masashi Beppu, Koichiro Tanaka, Takao Namiki
The development of IPCD method - Quick and easy preparation method for decoctions of Kampo formula inspired by the method of boiling powdered crude drugs in the Song period of China -
The 18th International Congress of Oriental Medicine, 2016, 4, 15–17, Okinawa, Japan

矢作忠弘、渥美聡孝、三宅克典、石内勘一郎、森永紀、伏見裕利、大山雅義、森川敏生、有田正規、田中謙、○牧野利明
歴代成書にある生薬の効能に関する記載のデータベース化
日本薬学会第136年会、2016,年3月28日(横浜);28AB-pm320

○石内勘一郎、藤原章雄、姜文平、呉金濱、北中進
Lycopodium serratum var. longipetiolatumより単離した新規アルカロイドの構造とマクロファージ泡沫化阻害活性
日本薬学会第136年会、2016,年3月28日(横浜);28AB-pm281


2007年業績
2008年業績
2009年業績
2010年業績
2011年業績
2012年業績
2013年業績
2014年業績
2015年業績
2017年業績

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