牧野論文リスト

2020

Kan'ichiro Ishiuchi, Dai Hirose, Taishi Kondo, Kohei Watanabe, Kazuyoshi Terasaka, Toshiaki Makino
Mariannamides A and B, new cyclic octapeptides isolated from Mariannaea elegans NBRC102301
Bioorg. Med. Chem. Lett. 30(4): 126946, 2020

Aki Yamada, Miku Kondo-Kaneko, Kan'ichiro Ishiuchi, Toshiaki Makino, Kazuyoshi Terasaka
Isolation and characterization of a novel glucosyltransferase involved in production of emodin-6-O-glucoside and rhaponticin in Rheum palmatum
Plant Biotechnol. 37(3): 293-299, 2020

Yoshihiko Nakatani, Kanako Negoro, Miki Yamauchi, Maki Katasho, Kei-ichiro Ishikura, Anna Iwaki, Kazuyo Tsukada, Marina Yamaguchi, Arata Uehara, Masato Yoshida, Kan'ichiro Ishiuchi, Toshiaki Makino, Masahiro Ohsawa, Taku Amano
Neoline, an active ingredient of the processed aconite root in Goshajinkigan formulation, targets Nav1.7 to ameliorate mechanical hyperalgesia in diabetic mice
J. Ethnopharmacol. 259: 112963, 2020

Kan’ichiro Ishiuchi, Ayesha Amber Syed, Yasuhiro Kosuge, Yukio Fujiwara, Toshiaki Makino, Dai Hirose
Decaturinol A, a new meroterpenoid, isolated from Penicillium decaturense RO050
Bioorg. Med. Chem. Lett. 30: 127307, 2020

Yasin Genc, Didem Sohretoglu, U. Sebnem Harput, Kan'ichiro Ishiuchi, Toshiaki Makino, Iclal Saracoglu
Chemical constitiuents of Plantago holosteum and evaluation of their chemotaxonomic significance
Chem. Natl. Comp. 56: 566–568, 2020

Tsukasa Fueki, Koichiro Tanaka, Kunihiko Obara, Ryudo Kawahara, Takao Namiki, Toshiaki Makino
The acrid raphides in tuberous root of Pinellia ternata have lipophilic character and are specifically denatured by ginger extract
J. Nat. Med. 74 (4), 722–731, 2020

Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki Makino
Suppressive effects of Hainosan (Painongsan) against biofilm production by Streptococcus mutans
Dentistry J. 8(3): 71, 2020

Masaaki Minami, Toshiaki Makino
Effects of Lonicera japonica flower bud extract on Citrobacter rodentium-induced digestive tract infection
Medicines. 7(9): 52, 2020

Xin Xu, Koshi Asai, Daiki Kato, Kan’ichiro Ishiuchi, Kewen Ding, Yoshiaki Tabuchi, Misato Ota, Toshiaki Makino
Honey isomaltose contributes to the induction of granulocyte-colony stimulating factor (G-CSF) secretion in the intestinal epithelial cells following honey heating
Sci. Rep. 10: 15178, 2020

Sakiko Nishikawa, Yasumichi Inoue, Yuka Hori, Chiharu Miyajima, Daisuke Morishita, Nobumichi Ohoka, Shigeaki Hida, Toshiaki Makino, Hidetoshi Hayashi
Anti-inflammatory activity of kurarinone involves induction of HO-1 via the KEAP1/NRF2 pathway
Antioxidants 9: 842, 2020

2019

Misato Ota, Kan’ichiro Ishiuchi, Xin Xu, Masaaki Minami, Yasutaka Nagachi, Maho Yagi-Utsumi, Yoshiaki Tabuchi, Shao-Qing Cai, Toshiaki Makino
Immunostimulatory effects and chemical characteristics of heated honey
J. Ethnopharmacol. 228(10): 11–17, 2019

Waka Nakayama, Yukio Fujiwara, Yasuhiro Kosuge, Orawan Monthakantirat, Kazumi Fujikawa, Santi Watthana, Susumu Kitanaka, Toshiaki Makino, Kan’ichiro Ishiuchi
Phlenumdines D and E, new Lycopodium alkaloids from Phlegmariurus nummulariifolius, and their regulatory effects on macrophage differentiation during tumor development
Phytochem. Lett. 39(1): 98–103, 2019

Aki Yamada, Kan’ichiro Ishiuchi, Toshiaki Makino, Hajime Mizukami, Kazuyoshi Terasaka
A glucosyltransferase specific for 4-hydroxy-2,5-dimethyl-3(2H)-furanone in strawberry
Biosci. Biotech. Biochem.83(1): 106–113, 2019

Kan’ichiro Ishiuchi, Osamu Morinaga, Takeshi Ohkita, Chuanting Tian, Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tsubasa Kondo, Tomoya Yasujima, Hiroaki Yuasa, Kiyoshi Minamizawa, Takao Namiki, Toshiaki Makino
18β-glycyrrhetyl-3-O-sulfate would be a causative agent of licorice-induced pseudoaldosteronism
Sci. Rep. 9: 1587, 2019

Masaaki Minami, Mineo Nakamura, Toshiaki Makino
Effect of Lonicera caerulea var. emphyllocalyx extracts on murine Streptococcus pyogenes infection by modulating immune system
BioMed Res. Int. 2019: 1797930, 2019

Toshiyuki Atsumi, Yumi Yokoyama, Takami Yokogawa, Toshiaki Makino, Isao Ohtsuka
Effects of crushed Schisandra Fruit on the content of lignans in Kampo decoction
J. Nat. Med. 73(2): 381–387, 2019

Vahap Murat Kutluay, Toshiaki Makino, Makoto Inoue, Iclal Saracoglu
New knowledge about old drugs; a cardenolide type glycoside with cytotoxic effect and unusual secondary metabolites from Digitalis grandiflora Miller
Fitoterapia 134: 73–80, 2019

Katsuhiko Masumoto, Zhiyang Quan, Kan’ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
Drug interaction between shoseiryuto extract or catechins and fexofenadine through organic anion-transporting polypeptide (OATP) 1A2 in vitro
Pharmacog. Mag. 15(61): 304–308, 2019

Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki Makino
In vitro effect of the traditional medicine Hainosan (Painongsan) on Porphyromonas gingivalis
Medicines 2019: 58, 2019

Vahap Murat Kutluay, Kan'ichiro Ishiuchi, Toshiaki Makino, Iclal Saracoglu
Cytotoxic phenylethanoid glycosides from Digitalis davisiana Heywood: Evaluation of structure activity relationships and chemotaxonomical significance of isolated compounds
Fitoterapia 135: 90–98, 2019

Fuzi Zhang, Kan’ichiro Ishiuchi, Akinori Sugiyama, Masahiro Ohsawa, Toshiaki Makino
B-ring-homo-tonghaosu, isolated from Chrysanthemum morifolium capitulum, acts as a peroxisome proliferator-activated receptor-γ agonist
J. Nat. Prod. 73(3): 497–503, 2019

Zeynep Doğan, Kan’ichiro Ishiuchi, Toshiaki Makino, İclal Saraçoğlu
Alpha-pyrone glycosides from Scutellaria salviifolia Benth
Turkish J. Chem. 43(3): 972–981, 2019

Yohei Tanimura, Masato Yoshida, Kan’ichiro Ishiuchi, Masahiro Ohsawa, Toshiaki Makino
Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats
J. Ethnopharmacol. 241: 111859, 2019

Zeynep Doğan, İclal Saraçoğlu, Kan’ichiro Ishiuchi, Toshiaki Makino
New acylated iridoid glucosides from Scutellaria glaphyrostachys Rech.f. and chemotaxonomic importance for the genus Scutellaria
Phytochem. Lett. 242: 112059, 2019

Misato Ota, Junko Nakazakia, Yoshiaki Tabuch, Takahiko Ono, Toshiaki Makino
Historical and pharmacological studies on rehmannia root processing– Trends in usage and comparison of the immunostimulatory effects of its products with or without steam processing and pretreatment with liquor
J. Ethnopharmacol. 242: 112059, 2019

Masaaki Minami, Hiroshi Takase, Mineo Nakamura, Toshiaki Makino
Methanol extract of Lonicera caerulea var. emphyllocalyx fruit has antibacterial and anti-biofilm activity against Streptococcus pyogenes in vitro
BioScience Trends. 13(2): 145–151, 2019104, 2019.

Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki Makino
Hainosan (painongsan) suppresses the biofilm formation of Porphyromonas gingivalis and Prevotella intermedia in vitro
Tradit. Kampo Med. 6(2): 79–87, 2019

Shin Takayama, Ryutaro Arita, Minoru Ohsawa, Akiko Kikuchi, Natsumi Saito, Hiromichi Yasui, Toshiaki Makino, Yoshiharu Motoo, Tadashi Ishii
Perspectives on the use of ninjin’yoeito in modern medicine: a review of randomized controlled trials
Evid. Based Complement. Alternat. Med. 2019: 9590260, 2019

Sakiko Nishikawa, Yuka Itoh, Muneshige Tokugawa, Yasumichi Inoue, Ken-ichi Nakashima, Yuka Hori, Chiharu Miyajima, Kou Yoshida, Daisuke Morishita, Nobumichi Ohoka, Makoto Inoue, Hajime Mizukami, Toshiaki Makino, Hidetoshi Hayashi
Kurarinone from Sophora flavescens roots triggers ATF4 activation and cytostatic effects through PERK phosphorylation
Molecules 24(17): 3110, 2019

Kanon Takahashi, Tetsuhiro Yoshino, Yasuhito Maki, Kan'ichiro Ishiuchi, Takao Namiki, Keiko Ogawa-Ochiai, Kiyoshi Minamizawa, Toshiaki Makino, Tomonori Nakamura, Masaru Mimura, Kenji Watanabe
Identification of glycyrrhizin metabolites in humans and of a potential biomarker of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study
Arch. Toxicol. 91(11): 3111–3119, 2019

Masaaki Minami, Hiroshi Takase, Mineo Nakamura, Toshiaki Makino
Effect of Lonicera caerulea var. emphyllocalyx fruit on biofilm formed by Porphylomonas gingivalis
BioMed Res. Int. 2019: 3547858, 2019

Masaaki Minami, Hiroshi Takase, Mineo Nakamura, Toshiaki Makino
Methanol extract of Lonicera caerulea var. emphyllocalyx fruit has anti-motility and anti-biofilm activity against enteropathogenic Escherichia coli
Drug Discov. Ther. 13(6): 335–342, 2019

笛木司、松岡尚則、李宣融、牧野利明、猪飼祥夫
『傷寒論』の薬匕（方寸匕、銭匕）の量値
漢方の臨床 66(10): 945-953, 2019

笛木司、谷村陽平、田中耕一郎、千葉浩輝、松岡尚則、並木隆雄、藤田康介、須永隆夫、別府正志、牧野利明
『宋板傷寒論』の未修治附子配合処方の煎煮時間と煎液に含まれるアコニチン型ジエステルアルカロイド量－処方中の乾姜と甘草が与える影響－
日本東洋医学雑誌 70(4)313–323, 2019

牧野利明
甘草の副作用，偽アルドステロン症の真の原因物質の探索
医学のあゆみ 270(8), 621-626, 2019

牧野利明
漢方薬の有効成分の体内動態
Hormone Frontier in Gynecology 26(4), 275-280, 2019

2018

Misato Ota, Yasutaka Nagachi, Kan'ichiro Ishiuchi, Yoshiaki Tabuchi, Feng Xu, Ming-Ying Shang, Shao-Qing Cai, Toshiaki Makino
Comparison of the inducible effects of licorice products with or without heat-processing and pre-treatment with honey on granulocyte colony-stimulating factor secretion in cultured enterocytes
J.Ethenopharmacol. 214(1): 1–7, 2018

Rie Iijima, Tomoki Watanabe, Kan'ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
Interactions between crude drug extracts used in Japanese traditional Kampo medicines and organic anion-transporting polypeptide 2B1
J. Ethenopharmacol. 214(1): 153–159, 2018

Misato Ota, Feng Xu, Yao-Li Li, Ming-Ying Shang, Toshiaki Makino, Shao-Qing Cai
Comparison of chemical constituents among licorice, roasted licorice, and roasted licorice with honey
J. Nat. Med. 72(1): 80–95, 2018

Yohta Shimato, Misato Ota, Kohshi Asai, Toshiyuki Atsumi, Yoshiaki Tabuchi, Toshiaki Makino
Comparison of byakujutsu (Atractylodes rhizome) and sojutsu (Atractylodes lancea rhizome) on anti-inflammatory and immunostimulative effects in vitro
J.Nat. Med.72(1): 192–201, 2018

Hui Sun, Le Yang, Meng-xi Li, Heng Fang, Ai-hua Zhang, Qi Song, Xing-yuan Liu, Jing Su, Meng-die Yu, Toshiaki Makino, Xi-junWang
UPLC-G2Si-HDMS untargeted metabolomics for identification of metabolic targets of Yin-Chen-Hao-Tang used as a therapeutic agent of dampness-heat jaundice syndrome
J Chromatogr B Analyt Technol Biomed Life Sci. 1081-1082(1):41­50, 2018

Junji Akaki, Shiori Tachi, Naoki Nakamura, Tetsuya Arai, Hiroo Yamasaki, Makoto Inoue, Toshiaki Makino
Promotive effect of Bofutsushosan (Fangfengtongshengsan) on lipid and cholesterol excretion in feces in mice treated with a high-fat diet
J.Ethenopharmacol. 220(1): 1–8, 2018

Masaaki Minami, Toru Konishi, Hiroshi Takase, Toshiaki Makino
Comparison between the effects of oral and intramuscular administration of Shin'iseihaito (Xinyiqingfeitang) in aStreptococcus pyoge-induced murine sinusitis model
Evid. Based Complement. Alternat. Med. 2018: 8901215, 2018

Kan’ichiro Ishiuchi, Dai Hirose, Takuma Suzuki, Waka Nakayama, Wen-Ping Jiang, Orawan Monthakantirat, Jin-Bin Wu, Susumu Kitanaka, Toshiaki Makino
Identification ofLycopodium alkaloids produced by an ultraviolet-irradiated strain ofParaboeremia, an endophytic fungus from longipetiolatum
J. Nat. Prod. 81(5): 1143–1147, 2018

Fuzi Zhang, Anna Iwaki, Kan’ichiro Ishiuchi, Akinori Sugiyama, Masahiro Ohsawa, Toshiaki Makino
Peroxisome proliferator-activated receptor-γ agonistic effect of Chrysanthemum indicum capitulum and its active ingredients
Pharmacog. Mag. 14(56): 461–464, 2018

Mai Nagasaka, Ryoko Hashimoto, Yasumichi Inoue, Kan’ichiro Ishiuchi, Michiyo Matsuno, Yuka Itoh, Muneshige Tokugawa, Nobumichi Ohoka, Daisuke Morishita, Hajime Mizukami, Toshiaki Makino, Hidetoshi Hayashi
Anti-tumorigenic activity of chrysin from Oroxylum indicum via non-genotoxic p53 activation through the ATM-Chk2 pathway
Molecules. 23(6), 1394, 2018

Masaaki Minami, Toru Konishi, Toshiaki Makino
Effect of hochuekkito (buzhongyiqitang) on nasal cavity colonization of methicillin-resistant Staphylococcus aureus in murine model
Medicines. 5, 83, 2018

Hao Ni, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
Inhibitory effect of Japanese traditional Kampo formula frequently prescribed in gynecological clinics on CYP3A4
Evid. Based Complement. Alternat. Med. 2018: 4259603, 2018

Osamu Morinaga, Kan’ichiro Ishiuchi, Takeshi Ohkita, Chuanting Tian, Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tomoya Yasujima, Hiroaki Yuasa, Toshiaki Makino
Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism
Sci. Rep. 8: 15568, 2018

Yuusuke Tashiro, Ryo Sakai, Tomoko Hirose-Sugiura, Yukio Kato, Hirotaka Matsuo, Tappei Takada, Hiroshi Suzuki, Toshiaki Makino
Effects of osthol isolated from Cnidium monnieri fruit on urate transporter 1
Molecules. 23(11) 2837, 2018

笛木司、吉田理人、田中耕一郎、千葉浩輝、加藤憲忠、並木隆雄、柴山周乃、藤田康介、須永隆夫、松岡尚則、別府正志、牧野利明
水質がウズ煎液中のアコニチン型ジエステルアルカロイド量に及ぼす影響
日本東洋医学雑誌、69(4): 336-345, 2018

2017

Shengli Gao, Hirotaka Kushida, Toshiaki Makino
Ginsenosides, the ingredients of root of Panax ginseng, are not the substrates but the inhibitors of sodium-glucose transporter 1 (SGLT1)
J. Nat. Med. 71(1): 131-138, 2017

Toru Konishi, Masaaki Minami, Toshiaki Makino
Antibacterial activity of Shin'iseihaito (Xinyiqingfeitang) and its components against methicillin-resistant Staphylococcus aureus
Pharmacogn. J. 9(1): 73-82, 2017

Masaaki Minami, Toru Konishi, Hiroshi Takase, Toshiaki Makino
Shin'iseihaito (Xinyiqingfeitang) suppresses the biofilm formation of Streptococcus pneumoniae in vitro
BioMed Res. Int.  2017: 4775709, 2017

Toshiaki Suzuki, Ayano Yamamoto, Masahiro Ohsawa, Yoshiharu Motoo, Hajime Mizukami, Toshiaki Makino
Effect of ninjin’yoeito and ginseng extracts on oxaliplatin-induced neuropathies in mice
J. Nat. Med. 71(4): 757-764, 2017

Lei Zhou, Qiang Zhang, Wen Qi, Shuai Yan, Jialin Qu, Toshiaki Makino, Dan Yuan
Identification of metabolites in human and rat urine after oral administration of Xiao-Qing-Long-Tang (XQLT) by using ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry
J. Sep. Sci. 40(18): 3582-3592, 2017

Keisuke Hagihara, Abbreviation of Kampo Formulations Group, Shuji Yakubo, Committee for Vocabulary in the Japan Society for Oriental Medicine, Takao Namiki
Abbreviation of kampo formulations and basic terminology in kampo medicine
Tradit. Kampo Med. 4(2) 65–88, 2017

Masaaki Minami, Toru Konishi, Ryoko Sakakibara, Taichi Imura, Mika Watanabe, Hideo Morita, Naoto Kanemaki, Toshiaki Makino
Antimicrobial effects of shin'iseihaito in vitro and clinical background factors of Staphylococcus aureus infection
Tradit. Kampo Med. 4(2), 111–115, 2017

矢作忠弘、石内勘一郎、渥美聡孝、三宅克典、森永 紀、伏見裕利、大山雅義、森川敏生、田中 謙、有田正規、牧野利明
歴代教科書・解説書に見られる生薬の効能に関する記載のデータベース化（1）
生薬学雑誌 71(1): 1-19

矢作忠弘、石内勘一郎、渥美聡孝、三宅克典、森永 紀、伏見裕利、大山雅義、森川敏生、田中 謙、有田正規、牧野利明
歴代教科書・解説書に見られる生薬の効能に関する記載のデータベース化（２）
生薬学雑誌 71(1): 20-36)

笛木司、田中耕一郎、牧野利明、松岡尚則、別府正志、岡田研吉、牧角和宏
原典版「神仙太一膏」の試作〜処方中の黄丹（鉛丹）でゴマ油は樹枝状に硬化する
漢方の臨床 64(4): 453-457, 2017

笛木司、田中耕一郎、牧野利明、松岡尚則、佐藤忠章、小池一男、頼建守、並木隆雄、千葉浩輝、別府正志、須永隆夫、岡田研吉、牧角和宏
『本草経集注』に記載された「桂」の基原を一考する
日本東洋医学雑誌 68(3): 281-290, 2017

2016

Toru Konishi, Masaaki Minami, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Antibacterial activity of Shin'iseihaito (Xin Yi Qing Fei Tang) against Streptococcus pneumoniae
Pharmacogn. J. 8(1): 20-23, 2016

Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito (xinyiqingfeitang) on murine allergic reaction induced by nasal sensitization
J. Trad. Comp. Med. 6(3) 252-256, 2016

Tsukasa Fueki, Megumi Sumino, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Koichiro Tanaka, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula (part 3) – Extracting efficiency of the IPCD method for volatile compounds –
Tradit. Kampo Med. 3(2): 157-161, 2016

Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Yuka Kitao, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain.  
J. Ethenopharmacol. 186(1): 44-52, 2016

Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito (xinyiqingfeitang) on murine allergic reaction induced by nasal sensitization
J. Trad. Comp. Med. 6(3) 252-256, 2016

Tsukasa Fueki, Koki Chiba, Toshiaki Makino, Takanori Matsuoka, Tadaaki Satou, Kazuo Koike, Koichiro Tanaka, Megumi Sumino, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula (part 4) – the IPCD method on Rhubarb and Aconite root –
Tradit. Kampo Med. 3(2): 170-173, 2016

笛木司、牧野利明、松岡尚則、別府正志、須永隆夫、田中耕一郎、並木隆雄
宋代の煮散法にヒントを得た簡便かつ成分抽出効率良好な煎薬調製法の開発（第２報）－ 生薬残渣の簡便な分離法 －          
日本東洋医学雑誌 67(2): 114-122, 2016

三巻祥浩，小林義典，牧野利明
生薬学担当教員による漢方教育に対する取り組み
薬学雑誌 136(3), 397-398, 2016

牧野利明
漢方の国際化時代における漢方教育のあり方
薬学雑誌 136(3), 411-415, 2016

2015年

Tsukasa Fueki, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Takao Sunaga, Koichiro Tanaka Koichi Nagamine, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula inspired by the method of boiling powdered crude drugs in the Song period of China
Tradit. Kampo Med. 2(2): 67–73, 2015

Toshiaki Suzuki, Ayano Yamamoto, Masahiro Ohsawa, Yoshiharu Motoo, Hajime Mizukami, Toshiaki Makino
Ninjin'yoeito and ginseng extract prevent oxaliplatin-induced neurodegeneration in PC12 cells
J. Nat. Med. 69(4): 531-537, 2015

Baiyang Zhao, Yutaka Tomoda, Hajime Mizukami, Toshiaki Makino
9-Oxo-(10E,12E)-octadecadienoic acid, a cytotoxic fatty acid ketodiene isolated from eggplant calyx, induces apoptosis in human ovarian cancer (HRA) cells
J. Nat. Med. 69(3): 296-302, 2015

Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito on lung colonization of pneumococcus in murine model
Afr. J. Tradit Complement. Altern. Med. 12(6): 131-139, 2015

松岡尚則、別府正志、田中耕一郎、牧野利明、並木隆雄
アイヌにおける附子の調剤と瞑眩    
醫譚、118: 7538-7552, 2015

笛木 司、田中耕一郎、並木隆雄、松岡尚則、牧野利明
ハンゲの刺激（イガイガ）原因物質〜最近の研究動向〜                                             
漢方の臨床 62(6), 977-982, 2015

牧野利明
漢方薬を使用するうえでの留意点
成人病と生活習慣病 45(2): 167-172, 2015

牧野利明
『今さら聞けない生薬・漢方薬』
医薬経済社（東京）、2015年、全195ページ

2014年

Kosei Tsukamoto, Kyosuke Yamamoto, Toshiaki Makino
Counteractive effect of Paeonia lactiflora root constituent mudanpioside E against suppressive effect of Shoseiryuto-extract on passive cutaneous anaphylaxis reaction in mice
J. Ethnopharmacol. 153(3): 884-889, 2014

Toshiaki Makino, Yusaku Shiraki, Hajime Mizukami
Interaction of Gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice
J. Nat. Med. 68(3): 505-512, 2014

Toshiaki Makino,
3-Monoglucuronyl glycyrrhretinic acid is a possible marker compound related to licorice-induced pseudoaldosteronism
Biol. Pharm. Bull. 37(6): 898-902, 2014

Masahiro Ohsawa, Saki Otake, Tomoyasu Murakami, Shohei Yamamoto, Toshiaki Makino, Hideki Ono
Gabapentin prevents oxaliplatin-induced mechanical hyperalgesia in mice
J. Pharmacol. Sci.125(3): 292-299, 2014

Lei Zhou, Wen Qi, Cong Xu, Toshiaki Makino, Dan Yuan
A rapid method for simultaneous determination of 52 marker compounds in Xiao-Qing-Long-Tang by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
J. Sep. Sci. 37(22): 3260–3267, 2014

笛木司、松岡尚則、牧野利明、並木隆雄、別府正志、山口秀敏、中田英之、頼建守、萩原圭祐、田中耕一郎、須永隆夫、長坂和彦、岡田研吉、岩井祐泉、牧角和宏
『宋板傷寒論』の権衡の検討〜生薬カスの吸着水量とマオウアルカロイドの煎出効率に着目して〜
日本東洋医学雑誌 65(2): 61-72, 2014

笛木司、松岡尚則、牧野利明、並木隆雄、別府正志、山口秀敏、中田英之、頼建守、萩原圭祐、田中耕一郎、長坂和彦、須永隆夫、李宜融、岡田研吉、岩井祐泉、牧角和宏
敦煌本に基づく『本草経集注』の権衡と方寸匕の量についての検討－傷寒論成立時代の度量衡－ 
日本東洋医学雑誌、65(1): 38-45, 2014

2013年

Hirotaka Yamashita, Toshiaki Makino, Naoki Inagaki, Mitsuhiko Nose, Hajime Mizukami
Assessment of relief from pruritus due to kampo medicines by using murine models of atopic dermatitis
J. Trad. Med. 30(3), 114-123, 2013

Fan Bai, Toshiaki Makino, Keiko Kono, Akito Nagatsu, Takahiko Ono, Hajime Mizukami
Calycosin and formononetin from astragalus root enhance dimethylarginine dimethylaminohydrolase 2 and nitric oxide synthase expressions in Madin Darby Canine Kidney II cells
J. Nat. Med. 67(4), 782-789, 2013

Toshiaki Makino, Misaki Kanemaru, Shuji Okuyama, Ryosuke Shimizu, Hisashi Tanaka, Hajime Mizukami
Anti-allergic effects of enzymatically modified isoquercitrin (α-oligoglucosyl quercetin 3-O-glucoside), quercetin 3-O-glucoside, α-oligoglucosyl rutin, and quercetin, when these substances were orally administered to mice
J. Nat. Med. 67(4), 881-886, 2013

Masayuki Sakiyama, Hirotaka Matsuo, Seiko Shimizu, Toshinori Chiba, Akiyoshi Nakayama, Yuzo Takada, Takahiro Nakamura, Tappei Takada, Emi Morita, Mariko Naito,·Kenji Wakai, Hiroki Inoue, Seishiro Tatsukawa, Junki Sato, Kazumi Shimono,  Toshiaki Makino, Takahiro Satoh, Hiroshi Suzuki, Yoshikatsu Kanai, Nobuyuki Hamajima, Yutaka Sakurai, Kimiyoshi Ichida, Toru Shimizu, Nariyoshi Shinomiya
A common variant of leucine-rich repeat containing 16A (LRRC16A) gene is associated with gout susceptibility
Human Cell 7(4): e35763, 2013

Hong Wang, Xue Bai, Jiahong Sun, Yoshihiro Kano, Toshiaki Makino, Dan Yuan
Metabolism and excretion of kakkalide and its metabolites in rat urine, bile, and feces as determined by HPLC/UV and LC/MS/MS
Planta Med. 79(16): 1552-1557, 2013

牧野利明
漢方薬理・最前線
phil漢方 2013, No. 41〜2019, No. 78

2012年

Jialin Qu, Jie Gao, Jiahong Sun, Lin Zhang, Toshiaki Makino, Dan Yuan
Pharmacokinetics of conjugated metabolites in rat plasma after oral administration of tectoridin.
J. Chromatogr. B. 902(1), 61-69, 2012

Toshiaki Makino, Kyoko Okajima, Rie Uebayashi, Nobuhiro Ohtake, Katsuhisa Inoue, Hajime Mizukami
3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2
J. Pharm. Exp. Ther. 342(2), 297-304, 2012

Yasuhiro Horita, Takemasa Takii, Tetsuya Yagi, Kenji Ogawa, Nagatoshi Fujiwara, Emi Inagaki, laurent kremer, Yasuo Sato, Ryuji Kuroishi, YooSa Lee, Toshiaki Makino, Hajime Mizukami, Tomohiro Hasegawa, Ryuji Yamamoto, and Kikuo Onozaki
Anti-tubercular activity of disulfiram, an anti-alcoholism drug, against multi-drug and extensively drug-resistant Mycobacterium tuberculosis isolates
Antimicrob. Agents Chemother. 56(8), 4140-4145, 2012

Fan Bai, Toshiaki Makino, Takahiko Ono, Hajime Mizukami
Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by DDAH-ADMA-NO pathway
J. Nat. Med. 66(4):583-590, 2012

牧野利明、三谷和男
漢方医療を支える「臨床生薬学」
phil漢方 37: 3-7, 2012

笛木司、松岡尚則、別府正志、山口秀敏、中田英之、頼建守、坂井由美、長坂和彦、牧野利明、並木隆雄、岡田研吉、岩井祐泉、牧角和宏
水質がマオウの煎液に及ぼす影響について　～特に日本と中国の上水道水の比較～
日本東洋医学雑誌 63(5): 313-321, 2012

松岡尚則、栗林秀樹、別府正志、山口秀敏、中田英之、阿南多美恵、笛木司、頼建守、岡田研吉、岩井祐泉、牧角和宏、三浦於菟、並木隆雄、牧野利明、秋葉哲生
薩摩旧薬園と生薬
漢方の臨床 59(6): 1083-1096, 2012

牧野利明
今さら聞けない生薬・漢方薬
医薬経済 2012年7月1日号～2015年1月16日号

2011年

Ayaka Sumi, Natsuko Y Hanada, Fan Bai, Toshiaki Makino, Hajime Mizukami, Takahiko Ono
Roles of coagulation pathway and factor Xa in the progression of diabetic nephropathy in db/db mice
Biol. Pharm. Bull. 34(6): 824-830, 2011

牧野利明
生薬学と医療薬学の融合～「臨床生薬学」の紹介
薬学雑誌 131(3): 375-382, 2011

牧野利明
漢方薬学教育を考える
漢方の臨床 58(1): 73, 2011

牧野利明、大嶽信弘
漢方薬の副作用～偽アルドステロン症のメカニズムとその発症予防策について
ファルマシア 47(5): 403-407, 2011

牧野利明、堀美智子
生活習慣病等の方へのかぜ薬の選択
Pharma Medica 29(7): 125-129, 2011

松岡尚則、栗林秀樹、別府正志、山口秀敏、中田英之、阿南多美恵、頼建守、岡田研吉、岩井祐泉、牧角和宏、三浦於菟、秋葉哲生、牧野利明、笛木司
海人湯と鷓鴣菜湯
漢方の臨床 58(11): 2263-2272, 2011

牧野利明
インフルエンザ感染症に対する漢方薬の効果
薬局 62(12): 74-78, 2011

牧野利明
漢方製剤に使用される注意するべき生薬
調剤と情報 17(12) 1731-1734, 2011

2010年

Katsuhiro Hayashi, Kyoko Shimura, Toshiaki Makino, Hajime Mizukami
Comparison of the contents in kampo decocion containing ephedra herb when prepared simply or by re-boiling method according to the traditional theory
J. Nat. Med. 64(1): 70-74, 2010

Toshiaki Makino, Toshihiro Togo, Hiromichi Yasui
Kampo Medicine and Japanese Acupuncture
J. Int. Soc. Oriental Med. 0: 10-21, 2010

牧野利明
「臨床生薬学」の歴史～創始者、山口広次の果たした功績
薬史学雑誌 45: 126-129 (2010)

牧野利明
生薬・漢方薬の基礎と臨床生薬学
明日の臨床 22: 11-18 (2010)

2009年

Hirotaka Yamashita, Daisuke Tasaki, Toshiaki Makino, Kunie Matsuoka, Mitsuhiko Nose, Naoki Inagaki, Hajime Mizukami
The role of IgE and repeated challenge in the induction of persistent increases in scratching behavior in a mouse model of allergic dermatitis
Eur. J. Pharmacol. 605(1-3):153-157, 2009

Toshiaki Makino, Keita Kato, Hajime Mizukami
Processed aconite root prevents cold-stress-induced hypothermia and immuno-suppression in mice
Biol. Pharm. Bull. 32(10):1741-1748, 2009

Toshiaki Makino, Ryosuke Shimizu, Misaki Kanemaru, Yukio Suzuki, Masamitsu Moriwaki, Hajime Mizukami
Enzymatically modified isoquercitrin, alpha-oligoglucosyl quercetin 3-O-glucoside, is absorbed more easily than other quercetin glycosides or aglycone after oral administration in rats
Biol. Pharm. Bull. 32(12): 2034-2040, 2009

Takahiko Ono, Toshiaki Makino
Basic study and clinical practice of Kampo medicines in chronic kidney disease (CKD): chronic glomerulonephritis and nephrosclerosis
J. Trad. Med. 26(5/6): 230-234, 2009

牧野利明
生薬、漢方薬、サプリメントと西洋薬間の相互作用（その１）
神奈川県薬剤師会会誌「薬壺」31(2): 2-6, 2009

牧野利明
生薬、漢方薬、サプリメントと西洋薬間の相互作用（その２）
神奈川県薬剤師会会誌「薬壺」31(3): 2-7, 2009

牧野利明
漢方薬学教育における「中薬学」の有用性
phil漢方 No. 28: 20, 2009

野田敏宏、高市和之、中村峰夫、唐澤豪貴、岡本泰範、水野智、栗原智仁、牧野利明、 平野剛、井関健
予防薬学を志向した保険薬局からの研究発信
薬学雑誌 219(12): 1469-1473, 2009

入江祥史・牧野利明
『漢方・中医学講座－臨床生薬学編～生薬の生産から臨床応用まで』
医歯薬出版（東京）, 2009

2008年

Toshiaki Makino, Minako Hamanaka, Hirotaka Yamashita and Hajime Mizukami
Effect of Bakumijiogan, an Herbal Formula in Traditional Chinese Medicine, on Atopic Dermatitis-Like Skin Lesions Induced by Mite Antigen in NC/Jic Mice
Biol. Pharm. Bull. 31(11): 2108-2113, 2008

Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue, Hajime Mizukami
Down-regulation of a hepatic transporter Mrp2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury
Drug Metab. Dispos. 36(7): 1438-1443, 2008

Toshiaki Makino, Atsuyuki Hishida, Yukihiro Goda, Hajime Mizukami
Comparison of major flavonoid contents in S. baicalensis, S. lateriflora and their commercial products
J. Nat. Med. 62(3): 292-297, 2008

加藤久幸、御影雅幸、姜東孝、牧野利明、篠原久仁子
生薬の基礎から供給まで
日本東洋医学雑誌 59(3): 397-425, 2008

牧野利明、水上　元
食品と医薬品の相互作用
FFIジャーナル 213(7): 635-644, 2008

2007年

Nobukazu Ryu, Hiroki Tanabe, Toshiaki Makino, Hajime Mizukami, Makoto Inoue
Shosaikoto (a Kampo medicine) modulates changes of cytochrome P450 caused by Mycobacterium butyricum injection
J. Nat, Med. 61(3): 342-348, 2007

Hirotaka Yamashita, Toshiaki Makino, Hajime Mizukami and Mitsuhiko Nose
Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
Eur. J. Pharmacol. 563: 233-239, 2007

牧野利明
「健康食品」の品質管理について
食品と包装　39(1): 30-34, 2007

2006年

Lingfeng Kong, Dan Yuan, Ying Chen, Jun Yin, Toshiaki Makino, Toshio Uno, Shaohui Zhang, Yoshihiro Kano
Quality evaluation of Echinacea species cultivated in China
Asian Journal of Traditional Medicines 1(1): 25-30, 2006

Keiko Kawashima, Yu Fujimura, Toshiaki Makino, Yoshihiro Kano
Pharmacological properties of traditional medicine (XXXII): Protective effects of Hangeshashinto and the combinations of its major constituents on gastric lesions in rats.
Biol. Pharm. Bull. 29(9): 1973-1975, 2006

Toshiaki Makino, Fumika Mizuno, Hajime Mizukami
Does a kampo medicine containing schisandra fruit affect pharmacokinetics of nifedipine like grapefruit juice?
Biol. Pharm. Bull. 29(10): 2065-2069, 2006

小野孝彦、牧野利明、劉寧、森幸子
柴苓湯の薬効解析：炎症を伴った線維化に対する抑制効果
漢方と最新治療　15(4): 305-313, 2006

2005年

Toshiaki Makino, Shin-ya Sasaki, Yoshiaki Ito, Yoshihiro Kano
Pharmacological properties of traditional medicine (XXX): Effects of Gyokuheifusan on murine antigen-specific antibody production.
Biol. Pharm. Bull. 28(1): 110-113, 2005

Toshiaki Makino, Takahiro Inagaki, Ken-ichi Komatsu, Yoshihiro Kano
Pharmacokinetic interactions between Japanese traditional kampo medicine and modern medicine (IV)-Effect of Kamisyoyosan and Tokisyakuyakusan on the pharmacokinetics of etizolam in rats.
Biol. Pharm. Bull. 28(2): 280-284, 2005

Nirmal Pugh, Premalatha Balachandran, Hemant Lata, Franck Dayan, Vaishali Joshi, Erdal Bedir, Toshiaki Makino, Rita Mores, Ikhlas Khan, David Pasco
Melanin: Dietary mucosal immune modulators from Echinacea and other botanical supplements.
Int. Immunopharmacol. 5(4): 637-647, 2005

牧野利明
玉屏風散の漢方薬物学的特性に関する研究
薬学雑誌　125(4): 349-354, 2005

Dan Yuan, Ying-ni Pan, Wen-wei Fu, Toshiaki Makino, Yoshihiro Kano
Chemical investigation of Salvia miltiorrihiza root and its phytomedicinal preparations
Chem. Pharm. Bull. 53(5): 508-514, 2005

Xijun Wang, Hui Sun, Yuling Fan, Lijing Li, Toshiaki Makino, Yoshihiro Kano
Analysis and bioactive evaluation of the compounds absorbed into blood after oral administration of the extracts of Vaccinium vitis-idaea in rat.
Biol. Pharm. Bull. 28(6), 1106-1108, 2005

牧野利明、中村峰夫、野田敏宏、高市和之、井関健
コエンザイムQ10含有健康食品における成分含量と溶解性
医療薬学 31(7): 505-510, 2005

Takahiko Ono, Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Eri Muso, Gisho Honda, and Toru Kita
Suppressive mechanisms of Sairei-to on mesangial matrix expansion in rat mesangioproliferative glomerulonephritis
Nephron Exp. Nephrol. 100(3):e132-142, 2005

Keiko Kawashima, Asano Nomura, Toshiaki Makino, Ken-ichi Saito, Yoshihiro Kano
Pharmacological Properties of Traditional Medicine (XXXI): Anxiolytic effect of Hangeshashinto and the combinations of its major constituents on rat experimental colitis.
J. Trad. Med. 22(2/3): 55-59, 2005

牧野利明
アメリカでの生薬・ハーブを用いた代替医療の現状と問題点
日本歯科東洋医学雑誌 24(1/2): 46-51, 2005

牧野利明
生薬、漢方薬の安全性と医療薬学的諸問題
薬用植物研究 28(1): 39-45, 2005

2004年

Toshiaki Makino, Yoshiaki Ito, Shin-ya Sasaki, Yu Fujimura, Yoshihiro Kano
Preventive and curative effects of Gyokuheifu-san, a formula of traditional Chinese medicine, on allergic rhinitis induced with Japanese cedar pollens in guinea pig
Biol. Pharm. Bull. 27 (4): 554-558, 2004

Toshiaki Makino, Takahiro Inagaki, Ken-ichi Komatsu, Yoshihiro Kano
Pharmacokinetic Interactions between Japanese Traditional Medicine (Kampo) and Modern Medicine (III). Effect of Sho-seiryu-to on the pharmacokinetics of azelastine hydrochloride in rats
Biol. Pharm. Bull. 27 (5): 670-673, 2004

Dan Yuan, Junna Mori, Ken-ich Komatsu, Toshiaki Makino, Yoshihiro Kano
An anti-aldosteronic diuretic component (drain dampness) in Polyporus sclerotium (猪苓)
Biol. Pharm. Bull. 27 (6): 867-870, 2004

Keiko Kawashima, Daishi Miyako, Yasuyuki Ishino, Toshiaki Makino, Ken-ichi Saito and Yoshihiro Kano
Anti-stress effects of 3,4,5-trimethoxycinnamic acid, an active constituent of roots of Polygara tenuifolia (Onji)
Biol. Pharm. Bull. 27(8): 1317-1319, 2004

Keiko Kawashima, Asano Nomura, Toshiaki Makino, Ken-ichi Saito and Yoshihiro Kano
Pharmacological properties of traditional medicine (XXIX): Effect of hange-shashin-to and the combinations of its herbal constituents on rat experimental colitis
Biol. Pharm. Bull. 27(10): 1599-1603, 2004

Takahiko Ono, Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Keiko Nomura, Eri Muso, Fujio Shimizu, Gisho Honda, and Toru Kita
Role of mesangial factor V expression in the crescent formation in rat Experimental mesangioproliferative glomerulonephritis
J. Pathol. 204(2): 229-238, 2004

Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Hitoshi Kusano, Katsuo Suyama, Eri Muso, Gisho Honda, Toru Kita, and Takahiko Ono
Coagulation in the mesangial area promotes extracellular matrix accumulation through factor V expression in mesangioproliferative glomerulonephritis in rats
Am. J. Physiol. 287(4): F612-F620, 2004

Ning Liu, Toshiaki Makino, Gisho Honda, Eri Muso, Toru Kita, Takahiko Ono
Suppressive effects of Sairei-to on mesangial proliferation in a rat model of glomerulonephritis
Clin. Exp. Nephrol. 8(3): 216-222, 2004

2003年

Toshiaki Makino, Takahiko Ono, Kotone Matsuyama, Fumiaki Nogaki, Shigeki Miyawaki, Gisho Honda, Eri Muso
Suppressive effects of Perilla frutescens on IgA nephropathy in HIGA mice
Nephrol. Dialysis Transplant. 18 (3): 484-490, 2003

Toshiaki Makino, Yasuyuki Furuta, Hannosuke Wakushima, Hajime Fujii, Ken-ichi Saito, Yoshihiro Kano
Anti-allergic effect of Perilla frutescens and its active constituents
Phytotherapy Res. 17 (3): 240-243, 2003

Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Yoshiharu Deguchi, Yoshihiro Kano
Pharmacokinetic and pharmacological interactions between ticlopidine hydrochloride and Kangen-Karyu, a Chinese traditional herbal medicine.
Phytotherapy Res. 17 (9): 1021-1024, 2003

牧野利明、山路誠一
薬用植物・生薬に関する副作用と薬害
薬用植物研究　26(1): 30-37, 2003

牧野利明
21世紀の薬学と生薬学をめざして
日本の科学者　38(12): 652-657, 2003

牧野利明
薬局方から見るアメリカでの生薬利用の歴史
社会薬学　22(2): 2-14, 2003

2002年

Toshiaki Makino, Gisho Honda, Takahiko Ono, Eri Muso
Effect of Perilla frutescens on production of nitric oxide and DNA synthesis of murine cultured vascular smooth muscle cell
Phytother Res. 16 (S1): 19-23, 2002

Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Ken-ichi Saito, Yoshihiro Kano
Effects of Kangen-Karyu on coagulation system and platelet aggregation in mice
Biol. Pharm. Bull. 25 (4): 523-525, 2002

Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Yoshiharu Deguchi, Yoshihiro Kano
Pharmacokinetic interactions between warfarin and Kangen-Karyu, a Chinese traditional herbal medicine, and their synergistic actions
J. Ethenopharmacol. 82 (1) 35-40, 2002

Takahiko Ono, Ning Liu, Hitoshi Kusano, Fumiaki Nogaki, Toshiaki Makino, Eri Muso, Shigetake Sasayama
Broad antiproliferative effects of benidipine on cultured human mesangial cells in cell-cycle phases.
Am. J. Nephrol. 22 (5-6): 581-586, 2002

Toshiaki Makino, Takahiko Ono, Ning Liu, Tomoko Nakamura, Eri Muso, Gisho Honda
Suppressive effects of rosmarinic acid on mesangial proliferative glomerulonephritis in rats
Nephron 92 (4): 898-904, 2002

小野孝彦、若杉博子、牧野利明、小野さかえ
民間薬の日本流入－健康食品・民間薬の安全性－
漢方と最新治療　11(1): 67-72, 2002

2001年

Toshiaki Makino, Fumiyuki Kiuchi, Michiho Ito, Takahiko Ono, Eri Muso, Gisho Honda
Inhibitory effect of decoction of Perilla frutescens on cultured murine mesangial cells and quantitative analysis of its active constituents
Planta Medica 67 (1): 24-28, 2001

Toshiaki Makino, Tomoko Nakamura, Takahiko Ono, Eri Muso, Gisho Honda
Suppressive effects of Perilla frutescens on mesangioproliferative glomerulonephritis in rats
Biol. Pharm. Bull. 24 (2): 172-175, 2001

Toshiaki Makino, Yasuyuki Furuta, Hajime Fujii, Takashi Nakagawa, Hannosuke Wakushima, Ken-ichi Saito, Yoshihiro Kano
Effect of oral treatment of Perilla frutescens and its constituents on type-I allergy in mice
Biol. Pharm. Bull. 24 (10): 1206-1209, 2001

2000年以前

Toshiaki Makino, Takahiko Ono, Eri Muso, Haruyoshi Yoshida, Gisho Honda, Shigetake Sasayama
Inhibitory effect of rosmarinic acid on the proliferation of cultured murine mesangial cells
Nephrol. Dialysis. Transplant. 15 (8): 1140-1145, 2000

牧野利明
生薬と起源植物の問題点－アリストロキア腎症を中心に－
Methods in Kampo Phamacology 5:50-54, 2000

Toshiaki Makino, Takahiko Ono, Michiho Ito, Eri Muso, Gisho Honda
Effect of Perilla frutescens extract on nitric oxide production by cultured murine mesangial cells
Biol. Pharm. Bull. 22 (5): 476-480, 1999

Toshiaki Makino, Takahiko Ono, Eri Muso, Gisho Honda
Suppressive effects of Perilla frutescens on spontaneous IgA nephropathy in ddY mice
Nephron 83 (1): 40-46, 1999

川添禎浩，牧野利明，有園幸司
内分泌かく乱物質（いわゆる環境ホルモン）と植物性エストロジェン
薬用植物研究　22(1): 24-35, 1999

Toshiaki Makino, Takahiko Ono, Eri Muso, Gisho Honda
Inhibitory effect of Perilla frutescens and its phenolic constituuents on cultured murine mesangial cell proliferation
Planta Medica 64 (6):541-545, 1998

牧野利明
漢方薬による腎障害－いわゆるChinese herbs nephropathyについて
薬用植物研究 21 (1): 35-39, 1998

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