List of Publications [ 1) Original
articles
2) Review articles 3) Book chapters 4) Proceedings ]
1) Original articles
- Shogo Akino, Tomoya Yasujima, Rei Shibutani, Takahiro Yamashiro, Hiroaki
Yuasa Involvement of proton-coupled SLC49A4-mediated transport in the export
of lysosomally trapped pyrilamine. Drug Metab. Dispos., 52, 19-25 (2024).
- Shogo Akino, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven
lysosomal pyridoxine exporter.
Life Sci. Alliance, 6, e202201629 (2023).
- Kohei Miyake, Tomoya Yasujima, Syunsuke Takahashi, Takahiro Yamashiro,
Hiroaki Yuasa
Identification of the amino acid residues involved in the species-dependent
differences in the pyridoxine transport function of SLC19A3.
J. Biol. Chem., 298, 102161 (2022).
- Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa
Animal species differences in the pyridoxine transport function of SLC19A3:
absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine.
Drug Metab. Pharmacokinet., 44, 100456 (2022).
- Yutaro Shinoda, Takahiro Yamashiro, Akira Hosooka, Tomoya Yasujima,
Hiroaki Yuasa
Functional characterization of human organic anion transporter 10
(OAT10/SLC22A13) as an orotate transporter.
Drug Metab. Pharmacokinet., 43, 100443 (2022).
- Kasin Yadunandam Anandam, Padmanabhan Srinivasan, Tomoya Yasujima, Saleh
Al-Juburi, Hamid M. Said
Proinflammatory cytokines inhibit thiamin uptake by human and mouse
pancreatic acinar cells: involvement of transcriptional mechanism(s).
Am. J. Physiol. Gastrointest. Liver Physiol., 320, G108-G116 (2021).
- Takahiro Yamashiro, Tomoya Yasujima, Hamid M. Said, Hiroaki Yuasa
pH-dependent pyridoxine transport by SLC19A2 and SLC19A3: implications for
absorption in acidic microclimates.
J. Biol. Chem., 295, 16998-17008 (2020).
- Kalidas Ramamoorthy, Kasin Yadunandam Anandam, Tomoya Yasujima,
Padmanabhan Srinivasan, Hamid M. Said
Posttranscriptional regulation of
thiamin transporter-1 expression by microRNA-200a-3p in pancreatic acinar
cells.
Am. J. Physiol. Gastrointest. Liver Physiol., 319, G323-G332 (2020).
- Tomoki Kabeya, Shinji Mima, Yuki Imakura, Toshihide Miyashita, Izumi
Ogura, Tadanori Yamada, Tomoya Yasujima, Hiroaki Yuasa, Takahiro Iwao, Tamihide
Matsunaga
Pharmacokinetic functions of human induced pluripotent stem cell-derived
small intestinal epithelial cells.
Drug Metab. Pharmacokinet., 35, 374-382 (2020).
- Risa Takenaka, Tomoya Yasujima, Junji Furukawa, Yosuke Hishikawa,
Takahiro Yamashiro, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa
Functional
analysis of the role of equilibrative nucleobase transporter 1
(ENBT1/SLC43A3) in adenine transport in HepG2 cells.
J. Pharm. Sci., 109,
2622-2628 (2020).
- Takahiro Yamashiro, Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue,
Hiroaki Yuasa
Identification of the amino acid residue responsible for the myricetin
sensitivity of human proton-coupled folate transporter.
Sci. Rep., 9, 18105 (2019).
- Kanichiro Ishiuchi, Osamu Morinaga, Takeshi Ohkita, Chuanting Tian,
Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tsubasa Kondo, Tomoya
Yasujima, Hiroaki Yuasa, Kiyoshi Minamizawa, Takao Namiki, Toshiaki Makino
18β-glycyrrhetyl-3-O-sulfate would be a causative agent to cause
licorice-induced pseudoaldosteronism.
Sci. Rep. 9, 1587 (2019).
- Osamu Morinaga, Kanichiro Ishiuchi, Takeshi Ohkita, Chuanting Tian,
Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tomoya Yasujima, Hiroaki
Yuasa, Toshiaki Makino
Isolation of a novel glycyrrhizin metabolite as a causal candidate compound
for pseudoaldosteronism.
Sci. Rep. 8, 15568 (2018).
- Tomoya Yasujima, Chihiro Murata, Yoshihisa Mimura, Tomoaki Murata,
Masahiko Ohkubo, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa
Urate transport function of rat sodium-dependent nucleobase transporter 1.
Physiol. Rep., 6, e13714 (2018).
- Takahito Furuya, Issey Takehara, Asuka Shimura, Hisanao Kishimoto,
Tomoya Yasujima, Kinya Ohta, Yoshiyuki Shirasaka, Hiroaki Yuasa, Katsuhisa
Inoue
Organic anion transporter 1 (OAT1/SLC22A6) enhances bioluminescence based on
D-luciferin-luciferase reaction in living cells by facilitating the
intracellular accumulation of D-luciferin.
Biochem. Biophys. Res. Commun., 495,
2152-2157 (2018).
- Takahiro Yamashiro, Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue,
Hiroaki Yuasa
Specific inhibitory effects of myricetin on human proton-coupled folate
transporter: comparison with its effects on rat proton-coupled folate
transporter and human riboflavin transporter 3.
Drug Metab. Pharmacokinet., 32, 311-314 (2017).
- Yoshihisa Mimura, Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki
Yuasa
Functional identification of plasma membrane monoamine transporter (PMAT/SLC29A4)
as an atenolol transporter sensitive to flavonoids contained in apple juice.
J. Pharm. Sci., 106, 2592-2598 (2017).
- Akiyoshi Nakayama, Hirofumi Nakaoka, Ken Yamamoto, Masayuki Sakiyama,
Amara Shaukat, Yu Toyoda, Yukinori Okada, Yoichiro Kamatani, Takahiro
Nakamura, Tappei Takada, Katsuhisa Inoue, Tomoya Yasujima, Hiroaki Yuasa,
Yuko Shirahama, Hiroshi Nakashima, Seiko Shimizu, Toshihide Higashino,
Yusuke Kawamura, Hiraku Ogata, Makoto Kawaguchi, Yasuyuki Ohkawa, Inaho
Danjoh, Atsumi Tokumasu, Keiko Ooyama, Toshimitsu Ito, Takaaki Kondo, Kenji
Wakai, Blanka Stiburkova, Karel Pavelka, Lisa K Stamp, Nicola Dalbeth,
Eurogout Consortium, Yutaka Sakurai, Hiroshi Suzuki, Makoto Hosoyamada, Shin
Fujimori, Takashi Yokoo, Tatsuo Hosoya, Ituro Inoue, Atsushi Takahashi,
Michiaki Kubo, Hiroshi Ooyama, Toru Shimizu, Kimiyoshi Ichida, Nariyoshi
Shinomiya, Tony R. Merriman, Hirotaka Matsuo
GWAS of clinically-defined gout and subtypes identifies multiple
susceptibility loci that include urate transporter genes.
Ann. Rheum. Dis., 76, 869-877 (2017).
- Junji Furukawa, Katsuhisa Inoue, Kinya Ohta, Tomoya Yasujima, Yoshihisa
Mimura, Hiroaki Yuasa
Role of equilibrative nucleobase transporter
1/SLC43A3 as a ganciclovir transporter in the induction of cytotoxic effect
of ganciclovir in a suicide gene therapy with herpes simplex virus thymidine
kinase.
J. Pharmacol. Exp. Ther., 360, 59-68 (2017).
- Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa,
Tamihide Matsunaga
Characteristic analysis of intestinal transport in enterocyte-like cells
differentiated from human induced pluripotent stem cells.
Drug Metab. Dispos., 44, 1662-1667 (2016).
- Tomoya Yasujima, Kosuke Saito, Rick Moore, Masahiko Negishi
Phenobarbital and insulin reciprocate activation of the nuclear receptor
constitutive androstane receptor through the insulin receptor.
J. Pharmacol. Exp. Ther., 357, 367-374 (2016).
- Junji Furukawa, Katsuhisa Inoue, Junya Maeda, Tomoya Yasujima, Kinya
Ohta, Yoshikatsu Kanai, Tappei Takada, Hirotaka Matsuo, Hiroaki Yuasa
Functional identification of SLC43A3 as an equilibrative nucleobase
transporter involved in purine salvage in mammals.
Sci. Rep., 5, 15057 (2015).
- Takahiro Yamashiro, Kinya Ohta, Katsuhisa Inoue, Mai Furumiya, Yayoi
Hayashi, Hiroaki Yuasa
Kinetic and time-dependent features of sustained inhibitory effect of
myricetin on folate transport by proton-coupled folate transporter.
Drug Metab. Pharmacokinet., 30, 341-346 (2015).
- Yoshihisa Mimura, Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki
Yuasa
Functional identification of organic cation transporter 1 as an
atenolol transporter sensitive to flavonoids.
Biochem. Biophys. Rep., 2,
166-171 (2015).
- Mai Furumiya, Takahiro Yamashiro, Katsuhisa Inoue, Chihiro Nishijima,
Kinya Ohta, Yayoi Hayashi, Hiroaki Yuasa
Sustained inhibition of
proton-coupled folate transporter by myricetin.
Drug Metab. Pharmacokinet.,
30, 154-159 (2015).
- Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue,
Hiroaki Yuasa: Competitive inhibition of AQP7-mediated glycerol transport by
glycerol derivatives. Drug Metab. Pharmacokinet., 29, 348 - 351, 2014.
- Mai Furumiya, Katsuhisa Inoue, Chihiro Nishijima, Takahiro Yamashiro,
Erina Inaoka, Kinya Ohta, Yayoi Hayashi, Hiroaki Yuasa: Noncompetitive
inhibition of proton-coupled folate transporter by myricetin. Drug Metab.
Pharmacokinet., 29, 312 - 316, 2014.
- Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue,
Hiroaki Yuasa: Functional characteristics of aquaporin 7 as a facilitative
glycerol carrier. Drug Metab. Pharmacokinet., 29, 244 - 248, 2014.
- Svetlana M. Nabokina, Katsuhisa Inoue, Veedamali S. Subramanian, Judith
E. Valle, Hiroaki Yuasa, Hamid M. Said: Molecular identification and
functional characterization of the human colonic thiamine pyrophosphate
transporter. J. Biol. Chem., 289, 4405 - 4416, 2014.
- Koji Kato, Haruyuki Mori, Tomoko Kito, Miyu Yokochi, Sumito Ito,
Katsuhisa Inoue, Atsushi Yonezawa, Toshiya Katsura, Yuji Kumagai, Hiroaki
Yuasa, Yoshinori Moriyama, Kenichi Inui, Hiroyuki Kusuhara, Yuichi Sugiyama: Investigation of endogenous compounds for assessing the drug
interactions in the urinary excretion involving multidrug and toxin
extrusion proteins. Pharm. Res., 31, 136 - 147, 2014.
- Mai Furumiya, Katsuhisa Inoue, Kinya Ohta, Yayoi Hayashi, Hiroaki Yuasa:
Transcriptional regulation of PCFT by KLF4, HNF4a,
CDX2 and C/EBPa: implication in its site-specific
expression in the small intestine. Biochem. Biophys. Res. Commun., 431, 158
- 163, 2013.
- Yuichiro Imamura, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara,
Katsuhisa Inoue, Hiroaki Yuasa, Takashi Izumi, Hiroyuki Kusuhara, Yuichi
Sugiyama: Effect of the fluoroquinolone antibacterial agent DX-619 on the
apparent formation and renal clearances of 6b-hydroxycortisol,
an endogenous probe for CYP3A4 inhibition, in healthy subjects. Pharm.
Res., 30, 447 - 457, 2013.
- Toshiaki Makino, Kyoko Okajima, Rie Uebayashi, Nobuhiro Ohtake,
Katsuhisa Inoue, Hajime Mizukami: 3-Monoglucuronyl-glycyrrhretinic acid is a
substrate of organic anion transporters expressed in tubular epithelial
cells and plays important roles in licorice-induced pseudoaldosteronism by
inhibiting 11β-hydroxysteroid dehydrogenase 2. J. Pharmacol. Exp. Ther.,
342, 297-304, 2012.
- Sumito Ito, Hiroyuki Kusuhara, Yuji Kumagai, Yoshinori Moriyama,
Katsuhisa Inoue, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Kazunari
Tanabe, Hiroaki Yuasa, Yuichi Sugiyama: N-Methylnicotinamide is an
endogenous probe for evaluation of drug-drug interactions involving
multidrug and toxin extrusions (MATE1 and MATE2-K). Clin. Pharmacol. Ther.,
92, 635 - 641, 2012.
- Masahiko Ohkubo, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa: Nicotinate
uptake by two kinetically distinct Na+-dependent carrier-mediated transport
systems in the rat small intestine. Drug Metab. Pharmacokinet., 27, 255 -
262, 2012.
- Sumito Ito, Hiroyuki Kusuhara, Miyu Yokochi, Junko Toyoshima, Katsuhisa
Inoue, Hiroaki Yuasa, Yuichi Sugiyama: Competitive inhibition of the luminal
efflux by multidrug and toxin extrusions, but not basolateral uptake by
organic cation transporter 2, is the likely mechanism underlying the
pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
J. Pharmacol. Exp. Ther., 340, 393 - 403, 2012.
- Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa:
Characterization of human OCT1-mediated transport of DAPI as a fluorescent
probe substrate. J. Pharm. Sci., 100, 4006 - 4012, 2011.
- Megumi Ishii, Kinya Ohta, Takahiro Katano, Kimihiko Urano, Jun Watanabe,
Aki Miyamoto, Katsuhisa Inoue, Hiroaki Yuasa: Dual functional characteristic
of human aquaporin 10 for solute transport. Cell. Physiol. Biochem., 27, 749
- 756, 2011.
- Hiroyuki Kusuhara, Sumito Ito, Yuji Kumagai, Min Jiang, Tomoyoshi
Shiroshita, Yoshinori Moriyama , Katsuhisa Inoue, Hiroaki Yuasa, Yuichi
Sugiyama: Effects of a MATE protein inhibitor, pyrimethamine, on the renal
elimination of metformin at oral microdose and at therapeutic dose in
healthy subjects. Clin. Pharmacol. Ther., 89, 837 - 844, 2011.
- Yuichiro Imamura, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara,
Osamu Okazaki, Takashi Izumi, Katsuhisa Inoue, Hiroaki Yuasa, Hiroyuki
Kusuhara, Yuichi Sugiyama: Prediction of fluoroquinolone-induced elevation
in serum creatinine levels: a case of drug-endogenous substance interaction
involving the inhibition of renal secretion. Clin. Pharmacol. Ther., 89, 81
- 88, 2011.
- Misaki Fujimura, Syunsuke Yamamoto, Tomoaki Murata, Tomoya Yasujima,
Katsuhisa Inoue, Kinya Ohta, and Hiroaki Yuasa: Functional characteristics
of the human ortholog of riboflavin transporter 2 and riboflavin-responsive
expression of its rat ortholog in the small intestine indicate its
involvement in riboflavin absorption. J. Nutr., 140, 1722 - 1727, 2010.
- Masashizu Nagahara, Yuko Waguri-Nagaya, Takaya Yamagami, Mineyoshi Aoyama, Toyohiro Tada, Katsuhisa Inoue, Kiyofumi Asai, Takanobu Otsuka:
TNF-a-induced aquaporin 9 in synoviocytes from patients with OA and RA. Rheumatology (Oxford), 49, 898 - 906, 2010.
- Sumito Ito, Hiroyuki Kusuhara, Yushun Kuroiwa, Chunyong Wu, Yoshinori Moriyama, Katsuhisa Inoue, Tsunenori Kondo, Hiroaki Yuasa, Hideki Nakayama, Shigeru
Horita, Yuichi Sugiyama: Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by
pyrimethamine. J. Pharmacol. Exp.
Ther., 333, 341 - 350, 2010.
- Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Munenori Ishimaru, Hiroaki Yuasa: Evaluation of
4',6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins. Drug
Metab. Dispos., 38, 715 - 721, 2010.
- Syunsuke Yamamoto, Katsuhisa Inoue, Tomoaki Murata, Syunsuke Kamigaso, Tomoya
Yasujima, Junya Maeda, Yukihiro Yoshida, Kinya Ohta, Hiroaki Yuasa: Identification and functional characterization of the first nucleobase
transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammals. J. Biol. Chem., 285, 6522 - 6531,
2010.
- Kinya Ohta, Katsuhisa Inoue, Tomoya Yasujima, Munenori Ishimaru, Hiroaki Yuasa: Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds. J.
Pharm. Pharm. Sci., 12, 388 - 396, 2009.
- Syunsuke Yamamoto, Katsuhisa Inoue, Kinya Ohta, Rui Fukatsu, Junya Maeda, Yukihiro Yoshida, Hiroaki
Yuasa: Identification and functional characterization of rat riboflavin transporter 2.
J. Biochem., 145, 437 - 443, 2009.
- Soichiro Matsushima, Kazuya Maeda, Katsuhisa Inoue, Kinya Ohta, Hiroaki Yuasa, Tsunenori Kondo, Hideki Nakayama, Shigeru
Horita, Hiroyuki Kusuhara, Yuichi Sugiyama: The inhibition of human multidrug and toxin extrusion 1
is involved in the drug-drug interaction caused by
cimetidine. Drug Metab. Dispos., 37, 555 - 559,
2009.
- Kinya Ohta, Yuichiro Imamura, Noriko Okudaira, Ryou Atsumi, Katsuhisa
Inoue, Hiroaki Yuasa: Functional characterization of multidrug and toxin extrusion protein 1 as a facilitative transporter for fluoroquinolones. J. Pharmacol. Exp. Ther. 328, 628 - 634, 2009.
- Yuriko Ohgusu, Kinya Ohta, Megumi Ishii, Takahiro Takano, Kimihiko Urano, Jun Watanabe, Katsuhisa Inoue, Hiroaki Yuasa: Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.
Drug Metab. Pharmacokinet., 23, 279
- 284, 2008.
- Nami Fujimoto, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa: Effect of glycerol-related compounds on carrier-mediated glycerol uptake in HCT-15 human colon cancer cell line. Drug
Metab. Pharmacokinet., 23, 216 - 220,
2008.
- Katsuhisa Inoue, Yasuhiro Nakai, Sayaka Ueda, Shunsuke Kamigaso, Kinya Ohta, Mai Hatakeyama, Yayoi Hayashi, Masaki Otagiri, Hiroaki Yuasa: Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model. Am. J. Physiol., 294, G660 - G668,
2008.
- Yasuhiro Nakai, Katsuhisa Inoue, Naoki Abe, Mai Hatakeyama, Kinya Ohta, Masaki Otagiri, Yayoi Hayashi, Hiroaki Yuasa: Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. J.
Pharmacol. Exp. Ther., 322, 469 - 476,
2007.
- Nami Fujimoto, Katsuhisa Inoue, Yuriko Ohgusu, Yayoi Hayashi, Hiroaki Yuasa: Enhanced uptake of glycerol by butyrate treatment in HCT-15 human colon cancer cell line. Drug
Metab. Pharmacokinet., 22, 195 - 198,
2007.
- Ryuji Kato, Hiroaki Yuasa, Katsuhisa Inoue, Takahiro Iwao, Kazuhiko Tanaka, Kazuya
Ooi, Yayoi Hayashi: Effect of Lactobacillus casei on the absorption of nifedipine from rat small intestine.
Drug Metab. Pharmacokinet., 22, 96 - 102, 2007.
- Kinya Ohta, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa: Molecular identification and functional characterization of rat multidrug and toxin extrusion type transporter 1 as an organic
cation/H+ antiporter in the kidney. Drug
Metab. Dispos., 34, 1868 -
1874,
2006.
- Kinya Ohta, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa: Carrier-mediated transport of glycerol in the perfused rat small intestine.
Biol. Pharm. Bull., 29, 785 - 789,
2006.
- Nami Fujimoto, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa: Glycerol uptake in
HCT-15 human colon cancer cell line by Na+-dependent
carrier-mediated transport. Biol. Pharm. Bull., 29, 150 - 154, 2006.
- Toyonori Kato, Yayoi Hayashi, Katsuhisa Inoue, Hiroaki Yuasa: Glycerol absorption by Na+-dependent carrier-mediated transport in the
closed loop of the rat small intestine. Biol. Pharm. Bull., 28, 553 - 555, 2005.
- Takahiro Iwao, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa, Jun Watanabe: Absorption
and metabolic extraction of diltiazem from the perfused rat small
intestine. Drug Metab. Pharmacokinet., 19, 430 - 437, 2004.
- Toyonori Kato, Yayoi Hayashi, Katsuhisa Inoue, Hiroaki Yuasa: Functional characterization
of the carrier-mediated transport system for glycerol in everted sacs of
the rat small intestine. Biol. Pharm. Bull., 27, 1826 - 1830, 2004.
- You-Jun Fei, Jin-Cai Liu, Katsuhisa Inoue, Lina Zhuang, Katsuya Miyake, Seiji Miyauchi, Vadivel Ganapathy: Relevance of NAC-2, an Na+-coupled
citrate transporter, to life span, body size and fat content in
Caenorhabditis elegans. Biochem.
J., 379, 191 - 198, 2004.
- Katsuhisa Inoue, You-Jun Fei, Lina Zhuang, Elangovan Gopal, Seiji Miyauchi, Vadivel Ganapathy: Functional features and genomic organization of mouse NaCT, a
sodium-coupled transporter for tricarboxylic acid cycle intermediates. Biochem. J., 378, 949 - 957, 2004.
- Kenji Tokui, Tsukasa Kimata, Kazuharu Uchida, Hiroaki Yuasa, Yayoi Hayashi, Takeharu Itatsu, Toshitaka Nabeshima: Dose adjustment strategy for oral microemulsion formulation
of cyclosporine: population pharmacokinetics-based analysis in kidney
transplant patients. Ther. Drug
Monit., 26, 287 - 294, 2004.
- Hiroaki Yuasa, Kaori Hamamoto, Shinya Dogu, Takeshi Marutani, Aki Nakajima, Toyonori Kato, Yayoi Hayashi, Katsuhisa Inoue, Jun Watanabe: Saturable absorption of glycerol in
the rat intestine. Biol. Pharm.
Bull., 26, 1633 - 1636, 2003.
- Shigemitsu Tomei, Mayumi Torimoto, Yayoi Hayashi, Katsuhisa Inoue, Hiroaki Yuasa, Jun Watanabe: Kinetic characterization of carrier-mediated transport systems for
D-glucose and taurocholate in the everted sacs of the rat colon. Biol.
Pharm. Bull., 26, 899 - 901,
2003.
- Shigemitsu Tomei, Yayoi Hayashi, Katsuhisa Inoue, Mayumi Torimoto, Yuri Ota, Kanako Morita, Hiroaki Yuasa, Jun Watanabe: Search for carrier-mediated transport systems in
the rat colon. Biol. Pharm. Bull.,
26, 274 - 277, 2003.
- Katsuhisa Inoue, Lina Zhuang, Dennis M. Maddox, Sylvia B. Smith, Vadivel Ganapathy: Human
sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as
a novel target for lithium action. Biochem.
J., 374, 21 - 26, 2003.
- You-Jun Fei, Katsuhisa Inoue, Vadivel Ganapathy: Structural and functional
characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1
and ceNaDC2) from Caenorhabditis elegans and their relevance to life span.
J. Biol. Chem., 278, 6136 - 6144,
2003.
- Takahiro Iwao, Katsuhisa Inoue, Yayoi Hayashi, Hiroaki Yuasa, Jun Watanabe: Metabolic
extraction of nifedipine during absorption from the rat small intestine. Drug
Metab. Pharmacokinet., 17, 546 -
553, 2002.
- Takatoshi Nakamura, Hiroaki Yuasa, Katsuhisa Inoue, Yayoi Hayashi, Jun Watanabe: Effect of
maleylated bovine serum albumin on the disposition of fractionated heparin
in rats. J. Pharm. Sci. Technol., Jpn., 62, 81 - 86, 2002.
- Takatoshi Nakamura, Hiroaki Yuasa, Katsuhisa Inoue, Yayoi Hayashi, Jun Watanabe: Uptake of
fractionated heparin by two types of scavenger-like receptors in rat liver
parenchymal cells in primary culture. Biol. Pharm. Bull., 25, 356 - 360,
2002.
- Narushi Takamatsu, Lynda S. Welage, Yayoi Hayashi, Ryuzo Yamamoto, Jeffrey L. Barnett, Vinod P. Shah, Lawrence J. Lesko, Chandrasekar Ramachandran, Gordon L. Amidon: Variability in
cimetidine absorption and plasma double peaks following oral
administration in the fasted state in humans: correlation with antral
gastric motility. Eur. J. Pharm.
Biopharm., 53, 37 - 47, 2002.
- Katsuhisa Inoue, Lina Zhuang, Vadivel Ganapathy: Human Na+-coupled
citrate transporter: primary structure, genomic organization, and
transport function. Biochem.
Biophys. Res. Commun., 299, 465 - 471, 2002.
- Katsuhisa Inoue, You-Jun Fei, Wei Huang, Lina Zhuang, Zhong Chen, Vadivel Ganapathy:
Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for citric acid cycle
intermediates. Biochem. J., 367,
313 - 319, 2002.
- Katsuhisa Inoue, Lina Zhuang, Dennis M. Maddox, Sylvia B. Smith, Vadivel Ganapathy:
Structure, function, and expression pattern of a novel sodium-coupled
citrate transporter (NaCT) cloned from mammalian brain. J. Biol. Chem., 277, 39469 - 39476,
2002.
- Shigemitsu Tomei, Hiroaki Yuasa, Katsuhisa Inoue, Jun Watanabe: Transport functions of
riboflavin carriers in the rat small intestine and colon: site difference
and effects of tricyclic-type drugs. Drug
Delivery, 8, 119 - 124, 2001.
- Narushi Takamatsu, Ok-Nam Kim, Lynda S. Welage, Nasir M. Idkaidek, Yayoi Hayashi, Jeffrey L. Barnett, Ryuzo Yamamoto, Elika Lipka, Hans Lennernäs, Ajaz. Hussain, Lawrence Lesko, Gordon L. Amidon: Human jejunal permeability of two polar drugs:
cimetidine and ranitidine. Pharm.
Res., 18, 742 - 744, 2001.
- Hiroaki Yuasa, Masato Hirobe, Shigemitsu Tomei, Jun Watanabe: Carrier-mediated
transport of riboflavin in the rat colon. Biopharm. Drug Dispos., 21, 77 - 82,
2000.
- Takatoshi Nakamura, Hiroaki Yuasa, Jun Watanabe: Uptake of fractionated heparin by
two types of scavenger receptors in isolated rat Kupffer cells. Biol.
Pharm. Bull., 23, 743 - 747,
2000.
- Jun Watanabe, Masami Haba, Chihiro Tanaka, Katsuhisa Inoue, Takatoshi Nakmura, Hiroaki Yuasa:
Scavenger receptor-mediated uptake of fractionated [3H]heparin
in rat peritoneal macrophages. Xenobio.
Metabol. Dispos., 15, 1 - 7, 2000.
- Yoichi Miyamoto, Takaaki Akaike, M. Samiul Alam, Katsuhisa Inoue, Takayoshi Hamamoto, Norisato Ikebe, Jun Yoshitake, Tatsuya Okamoto, Hiroshsi Maeda: Novel functions of human a1-protease inhibitor after S-nitrosylation: inhibition of cysteine
protease and antibacterial activity. Biochem. Biophys. Res. Commun. 267,
918 - 923, 2000.
- Tohru Amemiya, Satoshi Mizuno, Yayoi Hayashi, Hiroaki Yuasa, Jun Watanabe:
Absorption of vitamin K2 by dogs after oral
administration of a soft gelatin capsule formulation containing a new
emulsion-type vehicle. J. Pharm. Pharmacol., 51, 1375 - 1380, 1999.
- Tohru Amemiya, Satoshi Mizuno, Hiroaki Yuasa, Jun Watanabe: Emulsion type new
vehicle for soft gelatin capsule available for preclinical and clinical
trials: stabilization of new vehicle containing vitamin K2
with PEG 6000. Xenobio. Metabol.
Dispos., 14, 392 - 398, 1999.
- Tohru Amemiya, Satoshi Mizuno, Hiroaki Yuasa, Jun Watanabe: Emulsion type new
vehicle for soft gelatin capsule available for preclinical and clinical
trials: effects of PEG 6000 and PVP K30 on physicochemical stability of
new vehicle. Chem. Pharm. Bull.,
47, 492 - 497, 1999.
- Katsuhisa Inoue, Takaaki Akaike, Yoichi Miyamoto, Tatsuya Okamoto, Tomohiro Sawa, Masaki Otagiri, Shinnichiro Suzuki, Tetsuhiko Yoshimura, Hiroshi Maeda: Nitrosothiol formation catalyzed by
ceruloplasmin: implication for cytoprotective mechanism in vivo. J. Biol. Chem., 274, 27069 - 27075,
1999.
- Tohru Amemiya, Satoshi Mizuno, Hiroaki Yuasa, Jun Watanabe: Emulsion type new
vehicle available for preclinical and clinical trials: stability of
characteristics of particle size distribution of new vehicle. Xenobio. Metabol. Dispos., 13, 516 -
523, 1998.
- Jian Gu, Hiroaki Yuasa, Yayoi Hayashi, Jun Watanabe: First-pass metabolism of
5-fluorouracil in the perfused rat small intestine. Biol. Pharm. Bull., 21, 871 - 873,
1998.
- Hiroaki Yuasa, Jian Gu, Yayoi Hayashi, Jun Watanabe: First-pass metabolism of
5-fluorouracil in rats. J. Pharm. Pharmacol., 50, 1019 - 1025, 1998.
- Kenji Matsuda, Hiroaki Yuasa, Jun Watanabe: Fractional absorption of L-carnitine after oral administration in rats: evaluation of absorption
site and dose dependency. Biol. Pharm. Bull., 21, 752 - 755, 1998.
- Kenji Matsuda, Hiroaki Yuasa, Jun Watanabe: Physiological mechanism-based
analysis of dose-dependent gastrointestinal absorption of L-carnitine in
rats. Biopharm. Drug Dispos., 19,
465 - 472, 1998.
- Kenji Matsuda, Hiroaki Yuasa, Jun Watanabe: Dose dependency in
gastrointestinal absorption of cefatrizine: correlation between in vivo
and in situ. Biol. Pharm. Bull.,
21, 604 - 609, 1998.
- Tohru Amemiya, Satoshi Mizuno, Hiroaki Yuasa, Jun Watanabe: Development of
emulsion type new vehicle for soft gelatin capsule. I. Selection of
surfactants for development of new vehicle and its physicochemical
properties. Chem. Pharm. Bull., 46,
309 - 313, 1998.
- Julie K. Rhie, Yayoi Hayashi, Lynda S. Welage, Jeremy Frens, Randy J. Wald, Jeffrey L. Barnett, Gregory E. Amidon, Lakshmi Putcha, Gordon L. Amidon: Drug marker
absorption in relation to pellet size, gastric motility and viscous meals
in humans. Pharm. Res., 15, 233 -
238, 1998.
- Hiroaki Yuasa, Naomi Soga, Yukie Kimura, Jun Watanabe: Effect of aging on the
intestinal transport of hydrophilic drugs in the rat small intestine. Biol.
Pharm. Bull., 20, 1188 - 1192,
1997.
- Hiroaki Yuasa, Kenji Matsuda, Yukie Kimura, Naomi Soga, Jun Watanabe: Comparative
assessment of intestinal transport of hydrophilic drugs between small
intestine and large intestine. Drug
Delivery, 4, 269 - 272, 1997.
- Hiroaki Yuasa, Chiaki Kuno, Jun Watanabe: Effect of feeding condition on the
gastrointestinal absorption of D-xylose in rats. Pharm. Sci., 3, 357 - 360, 1997.
- Kimihiko Urano, Masami Haba, Hiroaki Yuasa, Jun Watanabe: Kinetic characterization
of binding and internalization of fractionated [3H]heparin
in rat liver parenchymal cells in primary culture. Biol. Pharm. Bull., 20, 680 - 683,
1997.
- Kimihiko Urano, Masami Haba, Hiroaki Yuasa, Jun Watanabe: Internalization of
fractionated 3H-heparin by the
scavenger-like receptor in rat liver parenchymal cells in primary culture.
Drug Delivery, 4, 181 - 185, 1997.
- Hiroaki Yuasa, Chiaki Kuno, Jun Watanabe: Comparative assessment of D-xylose
absorption between small intestine and large intestine. J. Pharm.
Pharmacol., 49, 26 - 29, 1997.
- Narushi Takamatsu, Lynda S. Welage, Nasir M. Idkaidek, Dong-Yue Liu, Peter I-Der Lee, Yayoi Hayashi, Julie K. Rhie, Hans Lenneräs, Jeffrey L. Barnett, Vinod P. Shah, Lawrence Lesko, Gordon L. Amidon: Human intestinal permeability of piroxicam,
propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion. Pharm. Res., 14, 1127 - 1132, 1997.
- Takaaki Akaike, Katsuhisa Inoue, Tatsuya Okamoto, Hirohito Nishino, Masaki Otagiri, Shigemoto Fujii, Hiroshi Maeda: Nanomolar quantification and identification of various
nitrosothiols by high performance liquid chromatography coupled with flow
reactors of metals and Griess reagent. J. Biochem., 122, 459 - 466, 1997.
- Hiroaki Yuasa, Kenji Matsuda, Jian Gu, Emiko Suzuki, Itsuko Yokouchi, Jun Watanabe:
Dose-dependent gastrointestinal absorption of 5-fluorouracil in rats in
vivo. Biol. Pharm. Bull., 19, 1494
- 1498, 1996.
- Masami Haba, Yukiko Minami, Hiroaki Yuasa, Jun Watanabe:
Macromolecule-macromolecule interaction in drug distribution. V. Effects
of plasma proteins on uptake of fractionated [3H]heparin
in isolated rat Kupffer cells. Biol. Pharm. Bull., 19, 1352 - 1356, 1996.
- Masami Haba, Kimihiko Urano, Hiroaki Yuasa, Jun Watanabe: Molecular weight
dependency in the uptake of fractionated [3H]heparin
in isolated rat Kupffer cells. Biol. Pharm. Bull., 19, 864 - 868, 1996.
- Hiroaki Yuasa, Chiaki Kuno, Jun Watanabe: Evaluation of the fractional
absorption of D-xylose by the analysis of gastrointestinal disposition
after oral administration in rats. Biol. Pharm. Bull., 19, 604 - 607, 1996.
- Jun Watanabe, Masami Haba, Kimihiko Urano, Hiroaki Yuasa: Uptake mechanism of
fractionated [3H]heparin in isolated rat
Kupffer cells: involvement of scavenger receptors. Biol. Pharm. Bull., 19, 581 - 586,
1996.
- Jun Watanabe, Kimihiko Urano, Masami Haba, Hiroaki Yuasa:
Macromolecule-macromolecule interaction in drug distribution. IV.
Molecular weight dependency in the interaction of fractionated [3H]heparin with plasma proteins. Biol. Pharm. Bull., 19, 287 - 290,
1996.
- Hiroaki Yuasa, Eiji Matsuhisa, Jun Watanabe: Intestinal brush border
transport mechanism of 5-fluorouracil in rats. Biol. Pharm. Bull., 19, 94 - 99, 1996.
- Jun Watanabe, Masami Haba, Hiroaki Yuasa: Uptake of fractionated 3H-heparin
by isolated rat Kupffer cells. Pharm.
Res., 12, 1092 - 1095, 1995.
- Hiroaki Yuasa, Koji Kawanishi, Jun Watanabe: Effects of ageing on the oral
absorption of D-xylose in rats: analysis of gastrointestinal disposition. J.
Pharm. Pharmacol., 47, 576 - 580,
1995.
- Hiroaki Yuasa, Koji Kawanishi, Jun Watanabe: Effects of ageing on the oral
absorption of D-xylose in rats. J. Pharm. Pharmacol., 47, 373 - 378, 1995.
- Hiroaki Yuasa, Kenji Matsuda, Jun Watanabe: Influence of anesthetic regimens
on the intestinal absorption of 5-fluorouracil in rats. Biol. Pharm. Bull., 18, 747 - 752,
1995.
- Jun Watanabe, Kimihiko Urano, Hiroya Muranishi, Masami Haba, Hiroaki Yuasa: Uptake of
low molecular weight fractionated [3H]heparin
by rat hepatocytes in the primary culture. Biol. Pharm. Bull., 18, 443 - 446,
1995.
- Hiroaki Yuasa, Wataru Numata, Shoji Ozeki, Jun Watanabe: Effect of dosing volume
on gastrointestinal absorption in rats: analysis of the gastrointestinal
disposition of L-glucose and estimation of in vivo intestinal membrane
permeability. J. Pharm. Sci., 84,
476 - 481, 1995.
- Akira Fukuhara, Teruko Imai, Katsuhisa Inoue, Masaki Otagiri: Effect of oral
multiple-dose administration of anti-inflammatory flurbiprofen chimera
drug on gastric lesion, other toxicities and disposition kinetics. Biol.
Pharm. Bull., 18, 140 - 147, 1995.
- Hiroaki Yuasa, Jun Watanabe: Influence of urethane anesthesia and abdominal
surgery on gastrointestinal motility in rats. Biol. Pharm. Bull., 17, 1309 - 1312,
1994.
- Hiroaki Yuasa, Michie Sekiya, Shoji Ozeki, Jun Watanabe: Gastric emptying-limited
oral absorption of a-linolenic acid
administered as a milk fat-globule membrane (MFGM) emulsion in rats. Biol.
Pharm. Bull., 17, 1262 - 1266,
1994.
- Hiroaki Yuasa, David Fleisher, Gordon L. Amidon: Noncompetitive inhibition of
cephradine uptake by enalapril in rabbit intestinal brush border membrane
vesicles: an enalapril specific inhibitory binding site on the peptide
carriers. J. Pharmacol.. Exp.
Ther., 269, 1107 - 1111, 1994.
- Hiroaki Yuasa, Michie Sekiya, Shoji Ozeki, Jun Watanabe: Evaluation of milk
fat-globule membrane (MFGM) emulsion for oral administration: absorption
of a-linolenic acid in rats and the effect of
emulsion droplet size. Biol. Pharm.
Bull., 17, 756 - 758, 1994.
- Junya Higuchi, Jun Watanabe, Yayoi Hayashi, Hiroaki Yuasa: Inter-organ relation
between salivary gland and kidney in lithium excretion. IV. Saturation of
inhibitory effect of NaCl on ductal reabsorption of Li+
in beagle dogs. Biol. Pharm. Bull.,
17, 356 - 358. 1994.
- Jun Watanbe, Hiromu Kondo, Hiroya Muranishi, Kimihiko Urano, Masami Haba, Hiroaki Yuasa:
Macromolecule-macromolecule interaction in drug distribution. III. Kinetic
characterization of the uptake of fractionated [3H]heparin
and the effect of plasma proteins in the perfused rat liver. Biol. Pharm. Bull., 16, 1035 - 1039,
1993.
- Jun Watanbe, Masami Haba, Hiroya Muranishi, Hiroaki Yuasa: Dose-dependent uptake
of radioactivity by liver parenchymal and non-parenchymal cells after
intravenous administration of fractionated [3H]heparin
to rats. Biol. Pharm. Bull., 16,
1031 - 1034, 1993.
- Jun Watanbe, Hiroya Muranishi, Masami Haba, Hiroaki Yuasa: Uptake of fluorescein
isothiocyanate (FITC)-fractionated heparin by rat parenchymal hepatocytes
in primary culture. Biol. Pharm.
Bull., 16, 939 - 941, 1993.
- Hiroaki Yuasa, Kenji Matsuda, Jun Watanabe: Influence of anesthetic regimens
on intestinal absorption in rats. Pharm.
Res., 10, 884 - 888, 1993.
- Jun Watanabe, Hiroya Muranishi, Hiroaki Yuasa: Uptake mechanism of fractionated
[3H]heparin in rat parenchymal
hepatocytes in primary culture: effect of transport inhibitors on the
uptake. Biol. Pharm. Bull., 16, 497
- 500, 1993.
- Hiroaki Yuasa, Gordon L. Amidon, David Fleisher: Peptide carrier-mediated
transport in intestinal brush border membrane vesicles of rats and
rabbits: cephradine uptake and inhibition. Pharm. Res., 10, 400 - 404, 1993.
- Jun Watanabe, Hiroya Muranishi, Hiroaki Yuasa, Shoji Ozeki:
Macromolecule-macromolecule interaction in drug distribution. II. Effect
of a-globulin on saturable uptake of
fractionated [3H]heparin by rat
parenchymal hepatocytes in primary culture. Chem. Pharm. Bull., 40, 3052 - 3055,
1992.
- Jun Watanabe, Hiroya Muranishi, Hiroaki Yuasa, Shoji Ozeki: Uptake of
fractionated [3H]heparin by rat
parenchymal hepatocytes in primary culture: effects of a-globulin,
temperature, and pH. J. Pharm. Sci., 81, 513 - 517, 1992.
- Jun Watanabe, Junya Higuchi, Yayoi Hayashi, Hiroaki Yuasa, Shoji Ozeki:
Inter-organ relation between salivary gland and kidney in lithium
excretion. III. Enhanced salivary and systemic clearance of Li+ by oral administration of NaCl in dogs. Chem.
Pharm. Bull., 38, 3428 - 3433,
1990.
- Jun Watanabe, Hiroya Muranishi, Hisashi Nakagaki, Hiroaki Yuasa, Shoji Ozeki:
Macromolecule-macromolecule interaction in drug distribution: effect of a-globulin concentration on the hepatic uptake of
fractionated 3H-heparin by perfused rat
liver. Chem. Pharm. Bull., 38,
2821 - 2824, 1990.
- Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano, Jun Watanabe: Relationship between in
vivo first-order intestinal absorption rate constant and the membrane
permeability clearance. J. Pharm. Sci., 78, 922 - 924, 1989.
- Jun Watanabe, Junya Higuchi, Yayoi Hayashi, Hiroaki Yuasa, Shoji Ozeki:
Inter-organ relation between salivary gland and kidney in lithium
excretion. II. Salivary, renal and systemic clearances of lithium under
continuous stimulation of salivation in water loaded dogs. J.
Pharmacobio-Dyn., 12, 537 - 543,
1989.
- Jun Watanabe, Hisashi Nakagaki, Hiroaki Yuasa, Shoji Ozeki: Investigation on
interaction of fractionated 3H-heparin
with plasma proteins by gel filtration chromatography. J. Pharmacobio-Dyn., 12, 416 - 422,
1989.
- Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano, Jun Watanabe: Relationship between the
first-order intestinal absorption rate constant in vivo and the membrane
permeability clearance in a perfusion system: an intragastric
administration method in vivo. J. Pharmacobio-Dyn., 12, 264 - 271, 1989.
- Jun Watanabe, Junya Higuchi, Yayoi Hayashi, Hiroaki Yuasa, Shoji Ozeki:
Inter-organ relation between salivary gland and kidney in lithium
excretion. I. Effects of continuous stimulation of salivation on salivary,
renal and systemic clearances of lithium in dog. J. Pharmacobio-Dyn., 11, 801 - 807,
1988.
- Jun Watanabe, Hitomi Murata, Junya Higuchi, Yayoi Hayashi, Kikuo Iwamoto, Hiroaki Yuasa, Shoji Ozeki: Dose-dependent salivary excretion following bolus
intravenous administration of lithium in dog. Chem. Pharm. Bull., 36, 3105 - 3112,
1988.
- Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano, Jun Watanabe: Comparative assessment of
the resistance of the unstirred water layer to solute transport between
two different intestinal perfusion systems. Biochim. Biophys. Acta, 938, 189 -
198, 1988.
- Hiroaki Yuasa, Yusei Miyamoto, Tatsuji Iga, Manabu Hanano, Jun Watanabe: Variation in
D-glucose uptake along the intestinal tract. J. Pharmacobio-Dyn., 10, 452 - 455,
1987.
- Takafumi Iwatsubo, Yusei Miyamoto, Yuichi Sugiyama, Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano: Effects of potential damaging agents on the microclimate-pH in the rat
jejunum. J. Pharm. Sci., 75, 1162
- 1165, 1986.
- Hiroaki Yuasa, Yusei Miyamoto, Tatsuji Iga, Manabu Hanano: Determination of kinetic
parameters of a carrier-mediated transport in the perfused intestine by
two-dimensional laminar flow model: effects of the unstirred water layer. Biochim. Biophys. Acta, 856, 219 -
230, 1986.
- Yusei Miyamoto, Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano: Determination of the
membrane permeability coefficient and the reflection coefficient by the
two-dimensional laminar flow model for intestinal perfusion experiments. Biochim. Biophys. Acta, 854, 191 -
197, 1986.
- Hiroaki Yuasa, Yusei Miyamoto, Tatsuji Iga, Manabu Hanano: Intestinal absorption by
carrier-mediated transports: two-dimensional laminar flow model. J. Theor. Biol., 119, 25 - 36, 1986.
- Hiroaki Yuasa, Yusei Miyamoto, Tatsuji Iga, Manabu Hanano: A laminar flow absorption
model for a carrier-mediated transport in the intestinal tract. J.
Pharmacobio-Dyn., 7, 604 - 606, 1984.
2) Review articles
- Hiroaki Yuasa, Tomoya Yasujima, Katsuhisa Inoue
Current understanding of the intestinal absorption of nucleobases and
analogs.
Biol. Pharm. Bull., 43, 1293-1300 (2020).
- Katsuhisa Inoue, Hiroaki Yuasa: Molecular basis for pharmacokinetics and
pharmacodynamics of methotrexate in rheumatoid arthritis therapy. Drug Metab.
Pharmacokinet., 29, 12 - 19, 2014.
- Hiroaki Yuasa, Katsuhisa Inoue, Yayoi Hayashi: Molecular and functional characteristics of proton-coupled folate transporter. J.
Pharm. Sci., 98, 1608 - 1616, 2009.
- Hiroaki Yuasa, Jun Watanabe: Are novel scavenger-like receptors involved in
the hepatic uptake of heparin? Drug Metab. Pharmacokinet., 18, 273 - 286, 2003.
- Jun Watanabe, Yayoi Hayashi, Hiroaki Yuasa: Biological half-lives of drugs in
human and experimental animals (VII): frequency distribution of half-life
values in normal adults. Ann. Rept. Pharm. Nagoya City Univ., 35, 53 -
106, 1987.
- Jun Watanabe, Yayoi Hayashi, Hiroaki Yuasa, Prasarn Manitpisitkul: Biological
half-lives of drugs in human and experimental animals (VI): the half-life
values in patients with liver disease. Ann. Rept. Pharm. Nagoya City
Univ., 34, 51 - 88, 1986.
3) Book chapters
- Hiroaki Yuasa: Drug absorption from the colon in situ. "Drug Absorption Studies: In Situ, In Vitro and In Silico Models", ed by Carsten Ehrhardt and Kwang-Jin Kim, Springer, New York, pp. 77 - 88 (Ch. 3), 2008.
4) Proceedings
- Jun Watanabe, Hiroshi Itoh, Yayoi Hayashi, Hiroaki Yuasa: Effects of sodium
chloride on salivary excretion of lithium in rats. "Lithium - 50
Years: Recent Advances in Biology and Medicine (Proceedings of the
Lithium-Lexington Symposium 1999)", ed. by Lucas, K. C., Becker, R.
W. and Gallicchio, V. S., Weidner Publishing Group (Gheshire Press),
Connecticut, pp. 81 - 91 (Ch. 9), 1999.
- Jun Watanbe, Kensaku Yoshida, Yayoi Hayashi, Hiroaki Yuasa: In vitro - in vivo
correlation in intestinal lithium absorption in rats. "The Biological
and Clinical Actions of Lithium: New Perspectives (Proceedings of the
Lithium-South Africa Symposium 1997)", ed. by Becker, W. R., Lucas,
K. C. and Gallicchio, V. S., Weidner Publishing Group (Gheshire Press),
Connecticut, pp. 175 - 184 (Ch. 15), 1998.
- Jun Watanabe, Tetsurou Nakamura, Yayoi Hayashi, Hiroaki Yuasa, Norihide Yoshioka, Koji Suzuki: Inhibitory effects of ion-selective ionophores on intestinal
absorption of lithium in rats. "Lithium: Biochemical and Clinical
Advances (Proceedings of the Malta Lithium Symposium 1995)", ed. by
Gallicchio, V. S. and Birch, N. J, Weidner Publishing Group (Gheshire
Press), Connecticut, pp. 201 - 209, 1996.
- Junya Higuchi, Jun Watanabe, Yayoi Hayashi, Hiroaki Yuasa, Shoji Ozeki:
Inter-organ relation between salivary gland and kidney in lithium
excretion: effects of continuous stimulation of salivation on lithium
clearances in dogs. J. Pharmacobio-Dyn., 12, s-58, 1989 (Proceedings of
the 19th Symposium on Drug Metabolism and Action, Osaka, 1988).
- Yusei Miyamoto, Hiroaki Yuasa, Tatsuji Iga, Manabu Hanano: Effect of the aqueous
diffusion layer on the intestinal drug absorption in situ. J.
Pharmacobio-Dyn., 8, s-130, 1985 (Proceedings of the 16th Symposium on
Drug Metabolism and Action, Gifu, 1984).
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