Publication of MAKINO Toshiaki
2020
Kan'ichiro Ishiuchi, Dai Hirose, Taishi Kondo, Kohei Watanabe, Kazuyoshi Terasaka, Toshiaki Makino
Mariannamides A and B, new cyclic octapeptides isolated from Mariannaea elegans NBRC102301
Bioorg. Med. Chem. Lett. 30(4): 126946, 2020
Aki Yamada, Miku Kondo-Kaneko, Kan'ichiro Ishiuchi, Toshiaki Makino, Kazuyoshi Terasaka
Isolation and characterization of a novel glucosyltransferase involved in production of emodin-6-O-glucoside and rhaponticin in Rheum palmatum
Plant Biotechnol. 37(3): 293-299, 2020
Yoshihiko Nakatani, Kanako Negoro, Miki Yamauchi, Maki Katasho, Kei-ichiro Ishikura, Anna Iwaki, Kazuyo Tsukada, Marina Yamaguchi, Arata Uehara, Masato Yoshida, Kan'ichiro Ishiuchi, Toshiaki Makino, Masahiro Ohsawa, Taku Amano
Neoline, an active ingredient of the processed aconite root in Goshajinkigan formulation, targets Nav1.7 to ameliorate mechanical hyperalgesia in diabetic mice
J. Ethnopharmacol. 259: 112963, 2020
Kan’ichiro Ishiuchi, Ayesha Amber Syed, Yasuhiro Kosuge, Yukio Fujiwara, Toshiaki Makino, Dai Hirose
Decaturinol A, a new meroterpenoid, isolated from Penicillium decaturense RO050
Bioorg. Med. Chem. Lett. 30: 127307, 2020
Yasin Genc, Didem Sohretoglu, U. Sebnem Harput, Kan'ichiro Ishiuchi, Toshiaki Makino, Iclal Saracoglu
Chemical constitiuents of Plantago holosteum and evaluation of their chemotaxonomic significance
Chem. Natl. Comp. 56: 566–568, 2020
Tsukasa Fueki, Koichiro Tanaka, Kunihiko Obara, Ryudo Kawahara, Takao Namiki, Toshiaki Makino
The acrid raphides in tuberous root of Pinellia ternata have lipophilic character and are specifically denatured by ginger extract
J. Nat. Med. 74 (4), 722–731, 2020
Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki Makino
Suppressive effects of Hainosan (Painongsan) against biofilm production by Streptococcus mutans
Dentistry J. 8(3): 71, 2020
Masaaki Minami, Toshiaki Makino
Effects of Lonicera japonica flower bud extract on Citrobacter rodentium-induced digestive tract infection
Medicines. 7(9): 52, 2020
Xin Xu, Koshi Asai, Daiki Kato, Kan’ichiro Ishiuchi, Kewen Ding, Yoshiaki Tabuchi, Misato Ota, Toshiaki Makino
Honey isomaltose contributes to the induction of granulocyte-colony stimulating factor (G-CSF) secretion in the intestinal epithelial cells following honey heating
Sci. Rep. 10: 15178, 2020
Sakiko Nishikawa, Yasumichi Inoue, Yuka Hori, Chiharu Miyajima, Daisuke Morishita, Nobumichi Ohoka, Shigeaki Hida, Toshiaki Makino, Hidetoshi Hayashi
Anti-inflammatory activity of kurarinone involves induction of HO-1 via the KEAP1/NRF2 pathway
Antioxidants 9: 842, 2020
2019
Misato Ota, Kan’ichiro Ishiuchi, Xin Xu, Masaaki Minami,
Yasutaka Nagachi, Maho Yagi-Utsumi, Yoshiaki Tabuchi, Shao-Qing Cai, Toshiaki
Makino
Immunostimulatory effects and chemical characteristics of heated honey
J. Ethnopharmacol. 228(10): 11–17, 2019
Waka Nakayama, Yukio Fujiwara, Yasuhiro Kosuge, Orawan
Monthakantirat, Kazumi Fujikawa, Santi Watthana, Susumu Kitanaka, Toshiaki
Makino, Kan’ichiro Ishiuchi
Phlenumdines D and E, new Lycopodium alkaloids from Phlegmariurus
nummulariifolius, and their regulatory effects on macrophage
differentiation during tumor development
Phytochem. Lett. 39(1): 98–103, 2019
Aki Yamada, Kan’ichiro Ishiuchi, Toshiaki Makino, Hajime
Mizukami, Kazuyoshi Terasaka
A glucosyltransferase specific for 4-hydroxy-2,5-dimethyl-3(2H)-furanone in
strawberry
Biosci. Biotech. Biochem.83(1): 106–113, 2019
Kan’ichiro Ishiuchi, Osamu Morinaga, Takeshi Ohkita, Chuanting
Tian, Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tsubasa Kondo, Tomoya
Yasujima, Hiroaki Yuasa, Kiyoshi Minamizawa, Takao Namiki, Toshiaki Makino
18β-glycyrrhetyl-3-O-sulfate would be a causative agent of
licorice-induced pseudoaldosteronism
Sci. Rep. 9: 1587, 2019
Masaaki Minami, Mineo Nakamura, Toshiaki Makino
Effect of Lonicera caerulea var. emphyllocalyx extracts on murine
Streptococcus pyogenes infection by modulating immune system
BioMed Res. Int. 2019: 1797930, 2019
Toshiyuki Atsumi, Yumi Yokoyama, Takami Yokogawa, Toshiaki
Makino, Isao Ohtsuka
Effects of crushed Schisandra Fruit on the content of lignans in Kampo
decoction
J. Nat. Med. 73(2): 381–387, 2019
Vahap Murat Kutluay, Toshiaki Makino, Makoto Inoue, Iclal
Saracoglu
New knowledge about old drugs; a cardenolide type glycoside with cytotoxic
effect and unusual secondary metabolites from Digitalis grandiflora Miller
Fitoterapia 134: 73–80, 2019
Katsuhiko Masumoto, Zhiyang Quan, Kan’ichiro Ishiuchi,
Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
Drug interaction between shoseiryuto extract or catechins and fexofenadine
through organic anion-transporting polypeptide (OATP) 1A2 in vitro
Pharmacog. Mag. 15(61): 304–308, 2019
Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki
Makino
In vitro effect of the traditional medicine Hainosan (Painongsan) on Porphyromonas
gingivalis
Medicines 2019: 58, 2019
Vahap Murat Kutluay, Kan'ichiro Ishiuchi, Toshiaki Makino,
Iclal Saracoglu
Cytotoxic phenylethanoid glycosides from Digitalis davisiana Heywood:
Evaluation of structure activity relationships and chemotaxonomical
significance of isolated compounds
Fitoterapia 135: 90–98, 2019
Fuzi Zhang, Kan’ichiro Ishiuchi, Akinori Sugiyama, Masahiro
Ohsawa, Toshiaki Makino
B-ring-homo-tonghaosu, isolated from Chrysanthemum morifolium capitulum, acts
as a peroxisome proliferator-activated receptor-γ agonist
J. Nat. Prod. 73(3): 497–503, 2019
Zeynep Doğan, Kan’ichiro Ishiuchi, Toshiaki Makino, İclal
Saraçoğlu
Alpha-pyrone glycosides from Scutellaria salviifolia Benth
Turkish J. Chem. 43(3): 972–981, 2019
Yohei Tanimura, Masato Yoshida, Kan’ichiro Ishiuchi,
Masahiro Ohsawa, Toshiaki Makino
Neoline is the active ingredient of processed aconite root against murine
peripheral neuropathic pain model, and its pharmacokinetics in rats
J. Ethnopharmacol. 241: 111859, 2019
Zeynep Doğan, İclal Saraçoğlu, Kan’ichiro Ishiuchi,
Toshiaki Makino
New acylated iridoid glucosides from Scutellaria glaphyrostachys Rech.f.
and chemotaxonomic importance for the genus Scutellaria
Phytochem. Lett. 242: 112059, 2019
Misato Ota, Junko Nakazakia, Yoshiaki Tabuch, Takahiko Ono,
Toshiaki Makino
Historical and pharmacological studies on rehmannia root processing– Trends in
usage and comparison of the immunostimulatory effects of its products with or
without steam processing and pretreatment with liquor
J. Ethnopharmacol. 242: 112059, 2019
Masaaki Minami, Hiroshi Takase, Mineo Nakamura, Toshiaki
Makino
Methanol extract of Lonicera caerulea var. emphyllocalyx fruit
has antibacterial and anti-biofilm activity against Streptococcus pyogenes
in vitro
BioScience Trends. 13(2): 145–151, 2019104, 2019.
Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki
Makino
Hainosan (painongsan) suppresses the biofilm formation of Porphyromonas
gingivalis and Prevotella intermedia in vitro
Tradit. Kampo Med. 6(2): 79–87, 2019
Shin Takayama, Ryutaro Arita, Minoru Ohsawa, Akiko Kikuchi,
Natsumi Saito, Hiromichi Yasui, Toshiaki Makino, Yoshiharu Motoo, Tadashi Ishii
Perspectives on the use of ninjin’yoeito in modern medicine: a review of
randomized controlled trials
Evid. Based Complement. Alternat. Med. 2019: 9590260, 2019
Sakiko Nishikawa, Yuka Itoh, Muneshige Tokugawa, Yasumichi
Inoue, Ken-ichi Nakashima, Yuka Hori, Chiharu Miyajima, Kou Yoshida, Daisuke
Morishita, Nobumichi Ohoka, Makoto Inoue, Hajime Mizukami, Toshiaki Makino,
Hidetoshi Hayashi
Kurarinone from Sophora flavescens roots triggers ATF4 activation and
cytostatic effects through PERK phosphorylation
Molecules 24(17): 3110, 2019
Kanon Takahashi, Tetsuhiro Yoshino, Yasuhito Maki,
Kan'ichiro Ishiuchi, Takao Namiki, Keiko Ogawa-Ochiai, Kiyoshi Minamizawa,
Toshiaki Makino, Tomonori Nakamura, Masaru Mimura, Kenji Watanabe
Identification of glycyrrhizin metabolites in humans and of a potential biomarker
of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study
Arch. Toxicol. 91(11): 3111–3119, 2019
Masaaki Minami, Hiroshi Takase, Mineo Nakamura, Toshiaki
Makino
Effect of Lonicera caerulea var. emphyllocalyx fruit on biofilm
formed by Porphylomonas gingivalis
BioMed Res. Int. 2019: 3547858, 2019
2018
Misato Ota, Yasutaka Nagachi, Kan'ichiro Ishiuchi, Yoshiaki
Tabuchi, Feng Xu, Ming-Ying Shang, Shao-Qing Cai, Toshiaki Makino
Comparison of the inducible effects of licorice products with or without
heat-processing and pre-treatment with honey on granulocyte colony-stimulating
factor secretion in cultured enterocytes
J.Ethenopharmacol. 214(1): 1–7, 2018
Rie Iijima, Tomoki Watanabe, Kan'ichiro Ishiuchi, Takashi
Matsumoto, Junko Watanabe, Toshiaki Makino
Interactions between crude drug extracts used in Japanese traditional Kampo
medicines and organic anion-transporting polypeptide 2B1
J.
Ethenopharmacol. 214(1): 153–159, 2018
Misato Ota, Feng Xu, Yao-Li Li, Ming-Ying Shang, Toshiaki
Makino, Shao-Qing Cai
Comparison of chemical constituents among licorice, roasted licorice, and
roasted licorice with honey
J.
Nat. Med. 72(1): 80–95, 2018
Yohta Shimato, Misato Ota, Kohshi Asai, Toshiyuki Atsumi,
Yoshiaki Tabuchi, Toshiaki Makino
Comparison of byakujutsu (Atractylodes rhizome) and sojutsu (Atractylodes
lancea rhizome) on anti-inflammatory and immunostimulative effects in vitro
J.Nat. Med.72(1): 192–201, 2018
Hui Sun, Le Yang, Meng-xi Li, Heng Fang, Ai-hua Zhang, Qi
Song, Xing-yuan Liu, Jing Su, Meng-die Yu, Toshiaki Makino, Xi-junWang
UPLC-G2Si-HDMS untargeted metabolomics for identification of metabolic targets
of Yin-Chen-Hao-Tang used as a therapeutic agent of dampness-heat jaundice syndrome
J
Chromatogr B Analyt Technol Biomed Life Sci. 1081-1082(1):4150,
2018
Junji Akaki, Shiori Tachi, Naoki Nakamura, Tetsuya Arai,
Hiroo Yamasaki, Makoto Inoue, Toshiaki Makino
Promotive effect of Bofutsushosan (Fangfengtongshengsan) on lipid and cholesterol
excretion in feces in mice treated with a high-fat diet
J.Ethenopharmacol. 220(1): 1–8, 2018
Masaaki Minami, Toru Konishi, Hiroshi Takase, Toshiaki
Makino
Comparison between the effects of oral and intramuscular administration of
Shin'iseihaito (Xinyiqingfeitang) in aStreptococcus pyoge-induced murine
sinusitis model
Evid.
Based Complement. Alternat. Med. 2018: 8901215, 2018
Kan’ichiro Ishiuchi, Dai Hirose,
Takuma Suzuki, Waka Nakayama, Wen-Ping Jiang, Orawan Monthakantirat, Jin-Bin
Wu, Susumu Kitanaka, Toshiaki Makino
Identification ofLycopodium alkaloids produced by
an ultraviolet-irradiated strain ofParaboeremia, an endophytic fungus
from longipetiolatum
J.
Nat. Prod. 81(5): 1143–1147, 2018
Fuzi Zhang, Anna Iwaki, Kan’ichiro Ishiuchi, Akinori
Sugiyama, Masahiro Ohsawa, Toshiaki Makino
Peroxisome proliferator-activated receptor-γ agonistic effect of Chrysanthemum
indicum capitulum and its active ingredients
Pharmacog. Mag. 14(56): 461–464, 2018
Mai Nagasaka, Ryoko Hashimoto, Yasumichi Inoue, Kan’ichiro
Ishiuchi, Michiyo Matsuno, Yuka Itoh, Muneshige Tokugawa, Nobumichi Ohoka,
Daisuke Morishita, Hajime Mizukami, Toshiaki Makino, Hidetoshi Hayashi
Anti-tumorigenic activity of chrysin from Oroxylum indicum via non-genotoxic
p53 activation through the ATM-Chk2 pathway
Molecules. 23(6), 1394, 2018
Masaaki Minami, Toru Konishi, Toshiaki Makino
Effect of hochuekkito (buzhongyiqitang) on nasal cavity colonization of
methicillin-resistant Staphylococcus aureus in murine model
Medicines. 5, 83, 2018
Hao Ni, Takashi Matsumoto, Junko Watanabe, Toshiaki
Makino
Inhibitory effect of Japanese traditional Kampo formula frequently prescribed
in gynecological clinics on CYP3A4
Evid. Based Complement. Alternat. Med. 2018: 4259603, 2018
Osamu Morinaga, Kan’ichiro Ishiuchi, Takeshi Ohkita,
Chuanting Tian, Asuka Hirasawa, Miaki Mitamura, Yasuhito Maki, Tomoya Yasujima,
Hiroaki Yuasa, Toshiaki Makino
Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for
pseudoaldosteronism
Sci. Rep. 8: 15568, 2018
Yuusuke Tashiro, Ryo Sakai, Tomoko Hirose-Sugiura, Yukio
Kato, Hirotaka Matsuo, Tappei Takada, Hiroshi Suzuki, Toshiaki Makino
Effects of osthol isolated from Cnidium monnieri fruit on urate transporter 1
Molecules. 23(11) 2837, 2018
2017
Shengli Gao, Hirotaka Kushida, Toshiaki Makino
Ginsenosides, the ingredients of root of Panax ginseng, are not the substrates but the inhibitors of sodium-glucose transporter 1 (SGLT1)
J. Nat. Med. 71(1): 131-138, 2017
Toru Konishi, Masaaki Minami, Toshiaki Makino
Antibacterial activity of Shin'iseihaito (Xinyiqingfeitang) and its components against methicillin-resistant Staphylococcus aureus
Pharmacogn. J. 9(1): 73-82, 2017
Masaaki Minami, Toru Konishi, Hiroshi Takase, Toshiaki Makino
Shin'iseihaito (Xinyiqingfeitang) suppresses the biofilm formation of Streptococcus pneumoniae in vitro
BioMed Res. Int. 2017: 4775709, 2017
Toshiaki Suzuki, Ayano Yamamoto, Masahiro Ohsawa, Yoshiharu Motoo, Hajime Mizukami, Toshiaki Makino
Effect of ninjin’yoeito and ginseng extracts on oxaliplatin-induced neuropathies in mice
J. Nat. Med. 71(4): 757-764, 2017
Lei Zhou, Qiang Zhang, Wen Qi, Shuai Yan, Jialin Qu, Toshiaki Makino, Dan Yuan
Identification of metabolites in human and rat urine after oral administration of Xiao-Qing-Long-Tang (XQLT) by using ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry
J. Sep. Sci. 40(18): 3582-3592, 2017
Keisuke Hagihara, Abbreviation of Kampo Formulations Group, Shuji Yakubo, Committee for Vocabulary in the Japan Society for Oriental Medicine, Takao Namiki
Abbreviation of kampo formulations and basic terminology in kampo medicine
Tradit. Kampo Med. 4(2) 65–88, 2017
Masaaki Minami, Toru Konishi, Ryoko Sakakibara, Taichi Imura, Mika Watanabe, Hideo Morita, Naoto Kanemaki, Toshiaki Makino
Antimicrobial effects of shin'iseihaito in vitro and clinical background factors of Staphylococcus aureus infection
Tradit. Kampo Med. 4(2), 111–115, 2017
Tsukasa Fueki, Koichiro Tanaka, Toshiaki Makino, Takanori Matsuoka, Tadaaki Satou, Kazuo Koike, Kenshu Lai, Takao Namiki, Koki Chiba, Masashi Beppu, Takao Sunaga, Kenkichi Okada, Kazuhiro Makizumi
Implications off the origin of “Gui” in the “Bencaojingjizhu”
Kampo Med. 68(3), 281-290, 2017 (in Japanese)
Tadahiro Yahagi, Kan’ichiro Ishiuchi, Toshiyuki Atsumc, Katsunori Miyake, Osamu Morinaga, Hirotoshi Fushimi, Masayoshi Oyama, Toshio Morikawa, Ken Tanaka, Masanori Arita, Toshiaki Makino
Database for the descriptions about the efficacies of crude drugs - Appearing in Successive Textbooks. Part I
Shoyakugaku Zasshi 71(1), 1-19, 2017 (in Japanese)
Tadahiro Yahagi, Kan’ichiro Ishiuchi, Toshiyuki Atsumc, Katsunori Miyake, Osamu Morinaga, Hirotoshi Fushimi, Masayoshi Oyama, Toshio Morikawa, Ken Tanaka, Masanori Arita, Toshiaki Makino
Database for the descriptions about the efficacies of crude drugs - Appearing in Successive Textbooks. Part II
Shoyakugaku Zasshi 71(1), 20-36, 2017 (in Japanese)
2016
Toru Konishi, Masaaki Minami, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Antibacterial activity of Shin'iseihaito (Xin Yi Qing Fei Tang) against Streptococcus pneumoniae
Pharmacogn. J. 8(1): 20-23, 2016
Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito (xinyiqingfeitang) on murine allergic reaction induced by nasal sensitization
J. Trad. Comp. Med. 6(3) 252-256, 2016
Tsukasa Fueki, Megumi Sumino, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Koichiro Tanaka, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula (part 3) – Extracting efficiency of the IPCD method for volatile compounds –
Tradit. Kampo Med. 3(2): 157-161, 2016
Toshiaki Suzuki, Keisuke Miyamoto, Naomi Yokoyama, Mayuko Sugi, Akina Kagioka, Yuka Kitao, Takumi Adachi, Masahiro Ohsawa, Hajime Mizukami, Toshiaki Makino
Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain.
J. Ethenopharmacol. 186(1): 44-52, 2016
Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito (xinyiqingfeitang) on murine allergic reaction induced by nasal sensitization
J. Trad. Comp. Med. 6(3) 252-256, 2016
Tsukasa Fueki, Koki Chiba, Toshiaki Makino, Takanori Matsuoka, Tadaaki Satou, Kazuo Koike, Koichiro Tanaka, Megumi Sumino, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula (part 4) – the IPCD method on Rhubarb and Aconite root –
Tradit. Kampo Med. 3(2): 170-173, 2016
Development of quick and high-yielding method for the preparation of decoctions, inspired by the “zhu san fa” of the Song period (part 2) - Easy method to separate muddy residue from decoction -
Tsukasa Fueki, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Takao Snhaga, Koichiro Tanaka. Takao Namiki
Kampo Med 67(2) 114-122, 2016 (in Japanese)
2015
Tsukasa Fueki, Toshiaki Makino<, Takanori Matsuoka, Masashi Beppu, Takao Sunaga, Koichiro Tanaka Koichi Nagamine, Takao Namiki
Quick and easy preparation method for decoctions of Kampo formula inspired by the method of boiling powdered crude drugs in the Song period of China
Tradit. Kampo Med. 2(2): 67–73, 2015
Toshiaki Suzuki, Ayano Yamamoto, Masahiro Ohsawa, Yoshiharu Motoo, Hajime Mizukami, Toshiaki Makino
Ninjin'yoeito and ginseng extract prevent oxaliplatin-induced neurodegeneration in PC12 cells
J. Nat. Med. 69(4): 531-537, 2015
Baiyang Zhao, Yutaka Tomoda, Hajime Mizukami, Toshiaki Makino
9-Oxo-(10E,12E)-octadecadienoic acid, a cytotoxic fatty acid ketodiene isolated from eggplant calyx, induces apoptosis in human ovarian cancer (HRA) cells
J. Nat. Med. 69(3): 296-302, 2015
Masaaki Minami, Tohru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino
Effect of shin'iseihaito on lung colonization of pneumococcus in murine model
Afr. J. Tradit Complement. Altern. Med. 12(6): 131-139, 2015
2014
Kosei Tsukamoto, Kyosuke Yamamoto, Toshiaki Makino
Counteractive effect of Paeonia lactiflora root constituent mudanpioside E against suppressive effect of Shoseiryuto-extract on passive cutaneous anaphylaxis reaction in mice
J. Ethnopharmacol. 153(3): 884-889, 2014
Toshiaki Makino, Yusaku Shiraki, Hajime Mizukami
Interaction of Gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice
J. Nat. Med. 68(3): 505-512, 2014
Toshiaki Makino,
3-Monoglucuronyl glycyrrhretinic acid is a possible marker compound related to licorice-induced pseudoaldosteronism
Biol. Pharm. Bull. 37(6): 898-902, 2014
Masahiro Ohsawa, Saki Otake, Tomoyasu Murakami, Shohei Yamamoto, Toshiaki Makino, Hideki Ono
Gabapentin prevents oxaliplatin-induced mechanical hyperalgesia in mice
J. Pharmacol. Sci., 125(3): 292-299, 2014
Lei Zhou, Wen Qi, Cong Xu, Toshiaki Makino, Dan Yuan
A rapid method for simultaneous determination of 52 marker compounds in Xiao-Qing-Long-Tang by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
J. Sep. Sci. 37(22): 3260–3267, 2014
Tsukasa Fueki, Takanori Matsuoka, Toshiaki Makino, Takao Namiki, Masashi Beppu, Hidetoshi Yamaguchi, Hideyuki Nakata, Kenshu Rai, Keisuke Hagihara, Koichiro Tanaka, Kazuhiko Nagasaka, Kenkichi Oada, Yusen Iwai, Kazuhiro Makizumi
The Investigation of metrological standard in “Songban Shanghanlun” : Focus on the absorbed Liquid in the Decoction Residues and the Extraction Efficiency of Ephedra-alkaloids.
Kampo Medicine 65(2): 61-72, 2014 (In Japanese)
Tsukasa Fueki, Takanori Matsuoka, Toshiaki Makino, Takao Namiki, Masashi Beppu, Hidetoshi Yamaguchi, Hideyuki Nakata, Kenshu Rai, Keisuke Hagihara, Koichiro Tanaka, Kazuhiko Nagasaka, Takao Sunaga, I-Jung Lee, Kenkichi Oada, Yusen Iwai, Kazuhiro Makizumi
The Weights in “Ben Cao Jing Ji Zhu (Dun Huang version)” and the Volume of “Fang Cun Bi” (one cun square spoon): The Weights and measures in the Period of the Establishment of “Shan Han Lun”
Kampo Medicine 65(1): 38-45, 2014 (In Japanese)
2013
Hirotaka Yamashita, Toshiaki Makino, Naoki Inagaki, Mitsuhiko Nose, Hajime Mizukami
Assessment of relief from pruritus due to kampo medicines by using murine models of atopic dermatitis
J. Trad. Med. 30(3), 114-123, 2013
Fan Bai, Toshiaki Makino, Keiko Kono, Akito Nagatsu, Takahiko Ono, Hajime Mizukami
Calycosin and formononetin from astragalus root enhance dimethylarginine dimethylaminohydrolase 2 and nitric oxide synthase expressions in Madin Darby Canine Kidney II cells
J. Nat. Med. 67(4), 782-789, 2013
Toshiaki Makino, Misaki Kanemaru, Shuji Okuyama, Ryosuke Shimizu, Hisashi Tanaka, Hajime Mizukami
Anti-allergic effects of enzymatically modified isoquercitrin (α-oligoglucosyl quercetin 3-O-glucoside), quercetin 3-O-glucoside, α-oligoglucosyl rutin, and quercetin, when these substances were orally administered to mice
J. Nat. Med. 67(4), 881-886, 2013
Masayuki Sakiyama, Hirotaka Matsuo, Seiko Shimizu, Toshinori Chiba, Akiyoshi Nakayama, Yuzo Takada, Takahiro Nakamura, Tappei Takada, Emi Morita, Mariko Naito,·Kenji Wakai, Hiroki Inoue, Seishiro Tatsukawa, Junki Sato, Kazumi Shimono, Toshiaki Makino, Takahiro Satoh, Hiroshi Suzuki, Yoshikatsu Kanai, Nobuyuki Hamajima, Yutaka Sakurai, Kimiyoshi Ichida, Toru Shimizu, Nariyoshi Shinomiya
A common variant of leucine-rich repeat containing 16A (LRRC16A) gene is associated with gout susceptibility
Human Cell 7(4): e35763, 2013
Hong Wang, Xue Bai, Jiahong Sun, Yoshihiro Kano, Toshiaki Makino, Dan Yuan
Metabolism and excretion of kakkalide and its metabolites in rat urine, bile, and feces as determined by HPLC/UV and LC/MS/MS
Planta Med. 79(16): 1552-1557, 2013
2012
Jialin Qu, Jie Gao, Jiahong Sun, Lin Zhang, Toshiaki Makino, Dan Yuan
Pharmacokinetics of conjugated metabolites in rat plasma after oral administration of tectoridin.
J. Chromatogr. B. 902(1), 61-69, 2012
Toshiaki Makino, Kyoko Okajima, Rie Uebayashi, Nobuhiro Ohtake, Katsuhisa Inoue, Hajime Mizukami
3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2
J. Pharm. Exp. Ther. 342(2), 297-304, 2012
Yasuhiro Horita, Takemasa Takii, Tetsuya Yagi, Kenji Ogawa, Nagatoshi Fujiwara, Emi Inagaki, laurent kremer, Yasuo Sato, Ryuji Kuroishi, YooSa Lee, Toshiaki Makino, Hajime Mizukami, Tomohiro Hasegawa, Ryuji Yamamoto, and Kikuo Onozaki
Anti-tubercular activity of disulfiram, an anti-alcoholism drug, against multi-drug and extensively drug-resistant Mycobacterium tuberculosis isolates
Antimicrob. Agents Chemother. 56(8), 4140-4145, 2012
Fan Bai, Toshiaki Makino, Takahiko Ono, Hajime Mizukami
Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by DDAH-ADMA-NO pathway
J. Nat. Med. 66(4):583-590, 2012
Toshiaki Makino, Kazuo Mitani
"Clinical Pharmacognosy" supports Kampo medicine
phil Kampo 37: 3-7, 2012 (in Japanese)
Tsukasa Fueki, Takanori Matsuoka, Masashi Beppu, Hidetoshi Yamaguchi, Hideyuki Natkata, Kenshu Rai, Yumi Sakai, Kazuhiko Nagasaka, Toshiaki Makino, Takao Namiki, Kenkichi Okada, Yusen Iwai, Kazuhiro Makizumi
Difference of water hardness on preparing the decoction of Ephedrae Herba : especially focused on the comparison of tap water between Japan and China
Kampo Medicine 63(5): 313-321, 2012 (in Japanses)
2011
Ayaka Sumi, Natsuko Y Hanada, Fan Bai, Toshiaki Makino, Hajime Mizukami, Takahiko Ono
Roles of coagulation pathway and factor Xa in the progression of diabetic nephropathy in db/db mice
Biol. Pharm. Bull. 34(6): 824-830, 2011
Toshiaki Makino
Integration of pharmacognosy and clinical pharmacy - Introduction of clicical pharmacognosy
Yakugakuzasshi 131(3): 375-382, 2011 (in Japanese)
Toshiaki Makino
My idea to educate kampo medicine in pharmaceutical school
J. Kampo Med. 58(1): 73, 2011 (in Japanese)
Toshiaki Makino, Nobuhiro Ohtake
Adverse effects of kampo medicine - mechanisms of licorice-induced pseudoaldosteronisms
Farumashia 47(5): 403-407, 2011 (in Japanese)
Others, 4 Japanese articles.
2010
Katsuhiro Hayashi, Kyoko Shimura, Toshiaki Makino, Hajime Mizukami
Comparison of the contents in kampo decocion containing ephedra herb when prepared simply or by re-boiling method according to the traditional theory
J. Nat. Med. 64(1): 70-74, 2010
Toshiaki Makino, Toshihiro Togo, Hiromichi Yasui
Kampo Medicine and Japanese Acupuncture
J. Int. Soc. Oriental Med. 0: 10-21, 2010
Toshiaki Makino
History of "clinical pharmacognosy" - Role of Hiroji Yamaguchi, the originator of clinical pharmacognosy
Yakushigaku Zasshi 45(2): 126-129, 2010 (in Japanese)
Toshiaki Makino
Introdution of Kampo medicine and clincal pharmacognosy.
Asu no Rinsho 22(2): 1-8, 2010 (in Japanese)
2009
Hirotaka Yamashita, Daisuke Tasaki, Toshiaki Makino, Kunie Matsuoka, Mitsuhiko Nose, Naoki Inagaki, Hajime Mizukami
The role of IgE and repeated challenge in the induction of persistent increases in scratching behavior in a mouse model of allergic dermatitis
Eur. J. Pharmacol. 605(1-3):153-157, 2009
Toshiaki Makino, Keita Kato, Hajime Mizukami
Processed aconite root prevents cold-stress-induced hypothermia and immuno-suppression in mice
Biol. Pharm. Bull. 32(10):1741-1748, 2009
Toshiaki Makino, Ryosuke Shimizu, Misaki Kanemaru, Yukio Suzuki, Masamitsu Moriwaki, Hajime Mizukami
Enzymatically modified isoquercitrin, alpha-oligoglucosyl quercetin 3-O-glucoside, is absorbed more easily than other quercetin glycosides or aglycone after oral administration in rats
Biol. Pharm. Bull. 32(12): 2034-2040, 2009
Takahiko Ono, Toshiaki Makino
Basic study and clinical practice of Kampo medicines in chronic kidney disease (CKD): chronic glomerulonephritis and nephrosclerosis
J. Trad. Med. 26(5/6): 230-234, 2009
Toshiaki Makino
Drug interactions between crude drugs, kampo medicines and dietary supplements 1
Journal of Kanagawa Pharmacists 31(2): 2-6, 2009 (in Japanese)
Toshiaki Makino
Drug interactions between crude drugs, kampo medicines and dietary supplements 2
Journal of Kanagawa Pharmacists 31(3): 2-7, 2009 (in Japanese)
Toshihiro Noda, Kazuyuki Takaichi, Mineo Nakamura, Hidetaka Karasawa, Yasunori Okamoto, Satoshi Mizuno, Tomohito Kurihara, Toshiaki Makino, Takeshi Hirano, Ken Iseki
Approach to alternative therapies in community pharmacy
Yakugaku Zasshi. 129(12):1469-1473, 2009 (in Japanese)
2008
Toshiaki Makino, Minako Hamanaka, Hirotaka Yamashita and Hajime Mizukami
Effect of Bakumijiogan, an Herbal Formula in Traditional Chinese Medicine, on Atopic Dermatitis-Like Skin Lesions Induced by Mite Antigen in NC/Jic Mice
Biol. Pharm. Bull. 31(11): 2108-2113, 2008
Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue, Hajime Mizukami
Down-regulation of a hepatic transporter Mrp2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury
Drug Metab. Dispos. 36(7): 1438-1443, 2008
Toshiaki Makino, Atsuyuki Hishida, Yukihiro Goda, Hajime Mizukami
Comparison of major flavonoid contents in S. baicalensis, S. lateriflora and their commercial products
J. Nat. Med. 62(3): 292-297, 2008
Hisayuki Kato, Masayuki Mikage, Donghyu Kang, Toshiaki Makino, Kuniko Shinohara
The problems of the herbal medicines
Kampo Med. 59(3) 397-425, 2008 (in Japanese)
Toshiaki Makino, Hajime Mizukami
Food-drug interactions
FFI Journal 213(7): 635-644, 2008 (in Japanese)
2007
Nobukazu Ryu, Hiroki Tanabe, Toshiaki Makino, Hajime Mizukami, Makoto Inoue
Shosaikoto (a Kampo medicine) modulates changes of cytochrome P450 caused by Mycobacterium butyricum injection
J. Nat, Med. 61(3): 342-348, 2007
Hirotaka Yamashita, Toshiaki Makino, Hajime Mizukami and Mitsuhiko Nose
Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
Eur. J. Pharmacol. 563(1-3): 233-239, 2007
Toshiaki Makino
Quality control for health food products
Foods and Packaging 39(1): 30-34, 2007 (in Japanese)
2006
Lingfeng Kong, Dan Yuan, Ying Chen, Jun Yin, Toshiaki Makino, Toshio Uno, Shaohui Zhang, Yoshihiro Kano
Quality evaluation of Echinacea species cultivated in China
Asian Journal of Traditional Medicines 1(1): 25-30, 2006
Keiko Kawashima, Yu Fujimura, Toshiaki Makino, Yoshihiro Kano
Pharmacological properties of traditional medicine (XXXII): Protective effects of Hangeshashinto and the combinations of its major constituents on gastric lesions in rats.
Biol. Pharm. Bull. 29(9): 1973-1975, 2006
Toshiaki Makino, Fumika Mizuno, Hajime Mizukami
Does a kampo medicine containing schisandra fruit affect pharmacokinetics of nifedipine like grapefruit juice?
Biol. Pharm. Bull. 29(10):2065-2069, 2006
Takahiko Ono, Ning Liu, Toshiaki Makino, Noriko Mori
Analysis of therapeutic mechanisms in Saireito: Inhibitory effect on fibrosis accompanied with inflammation. (in Japanese)
Kampo & the Newest Therapy 15(4): 305-313, 2006
2005
Toshiaki Makino, Shin-ya Sasaki, Yoshiaki Ito, Yoshihiro Kano
Pharmacological properties of traditional medicine (XXX): Effects of Gyokuheifusan on murine antigen-specific antibody production.
Biol. Pharm. Bull. 28(1): 110-113, 2005
Toshiaki Makino, Takahiro Inagaki, Ken-ichi Komatsu, Yoshihiro Kano
Pharmacokinetic interactions between Japanese traditional kampo medicine and modern medicine (IV)-Effect of Kamisyoyosan and Tokisyakuyakusan on the pharmacokinetics of etizolam in rats.
Biol. Pharm. Bull. 28(2): 280-284, 2005
Nirmal Pugh, Premalatha Balachandran, Hemant Lata, Franck Dayan, Vaishali Joshi, Erdal Bedir, Toshiaki Makino, Rita Mores, Ikhlas Khan, David Pasco
Melanin: Dietary mucosal immune modulators from Echinacea and other botanical supplements.
Int. Immunopharmacol. 5(4): 637-647, 2005
Toshiaki Makino
Pharmacological properties of Gyokuheifusan, a traditional Kampo medicinal formula (In Japanese)
Yakugaku Zasshi 125(4): 349-354, 2005
Dan Yuan, Ying-ni Pan, Wen-wei Fu, Toshiaki Makino, Yoshihiro Kano
Chemical investigation of Salvia miltiorrihiza root and its phytomedicinal preparations
Chem. Pharm. Bull. 53(5): 508-514, 2005
Xijun Wang, Hui Sun, Yuling Fan, Lijing Li, Toshiaki Makino, Yoshihiro Kano
Analysis and bioactive evaluation of the compounds absorbed into blood after oral administration of the extracts of Vaccinium vitis-idaea in rat.
Biol. Pharm. Bull. 28(6), 1106-1108, 2005
Toshiaki Makino, Mineo Nakamura, Toshihiro Noda, Kazuyuki Takaichi, Ken Iseki
Solubility characteristics and the content of coenzyme Q10 preparations as dietary supplements available in Japanese market (in Japanese)
Jap. J. Pharmaceu. Health Care Sci. 31(7): 505-510, 2005
Takahiko Ono, Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Eri Muso, Gisho Honda, and Toru Kita
Suppressive mechanisms of Sairei-to on mesangial matrix expansion in rat mesangioproliferative glomerulonephritis
Nephron Exp. Nephrol. 100(3):e132-142, 2005
Keiko Kawashima, Asano Nomura, Toshiaki Makino, Ken-ichi Saito, Yoshihiro Kano
Pharmacological properties of traditional medicine (XXXI): Anxiolytic effect of Hangeshashinto and the combinations of its major constituents on rat experimental colitis.
J. Trad. Med. 22(2/3): 55-59, 2005
Toshiaki Makino
The present state and provlems of herbal medicine and dietary supplements in United States (in Japanese)
J. Jap. Dental Soc. Oriental Med. 24(1/2): 46-51, 2005
Toshiaki Makino
Safety control for crude drugs and Kampo medicines and its clinicalpharmaceutical problems (in Japanese)
Jap. J. Medicinal Plants 28(1): 39-45, 2005
2004
Toshiaki Makino, Yoshiaki Ito, Shin-ya Sasaki, Yu Fujimura, Yoshihiro Kano
Preventive and curative effects of Gyokuheifu-san, a formula of traditional Chinese medicine, on allergic rhinitis induced with Japanese cedar pollens in guinea pig
Biol. Pharm. Bull. 27 (4): 554-558, 2004
Toshiaki Makino, Takahiro Inagaki, Ken-ichi Komatsu, Yoshihiro Kano
Pharmacokinetic Interactions between Japanese Traditional Medicine (Kampo) and Modern Medicine (III). Effect of Sho-seiryu-to on the pharmacokinetics of azelastine hydrochloride in rats
Biol. Pharm. Bull. 27 (5): 670-673, 2004
Dan Yuan, Junna Mori, Ken-ich Komatsu, Toshiaki Makino, Yoshihiro Kano
An anti-aldosteronic diuretic component (drain dampness) in Polyporus sclerotium
Biol. Pharm. Bull. 27 (6): 867-870, 2004
Keiko Kawashima, Daishi Miyako, Yasuyuki Ishino, Toshiaki Makino, Ken-ichi Saito and Yoshihiro Kano
Anti-stress effects of 3,4,5-trimethoxycinnamic acid, an active constituent of roots of Polygara tenuifolia (Onji)
Biol. Pharm. Bull. 27(8): 1317-1319, 2004
Keiko Kawashima, Asano Nomura, Toshiaki Makino, Ken-ichi Saito and Yoshihiro Kano
Pharmacological properties of traditional medicine (XXIX): Effect of hange-shashin-to and the combinations of its herbal constituents on rat experimental colitis
Biol. Pharm. Bull. 27(10): 1599-1603, 2004
Takahiko Ono, Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Keiko Nomura, Eri Muso, Fujio Shimizu, Gisho Honda, and Toru Kita
Role of mesangial factor V expression in the crescent formation in rat Experimental mesangioproliferative glomerulonephritis
J. Pathol. 204(2): 229-238, 2004
Ning Liu, Toshiaki Makino, Fumiaki Nogaki, Hitoshi Kusano, Katsuo Suyama, Eri Muso, Gisho Honda, Toru Kita, and Takahiko Ono
Coagulation in the mesangial area promotes extracellular matrix accumulation through factor V expression in mesangioproliferative glomerulonephritis in rats
Am. J. Physiol. 287(4): F612-F620, 2004
Ning Liu, Toshiaki Makino, Gisho Honda, Eri Muso, Toru Kita, Takahiko Ono
Suppressive effects of Sairei-to on mesangial proliferation in a rat model of glomerulonephritis
Clin. Exp. Nephrol. 8(3): 216-222, 2004
2003
Toshiaki Makino, Takahiko Ono, Kotone Matsuyama, Fumiaki Nogaki, Shigeki Miyawaki, Gisho Honda, Eri Muso
Suppressive effects of Perilla frutescens on IgA nephropathy in HIGA mice
Nephrol. Dialysis Transplant. 18 (3): 484-490, 2003
Toshiaki Makino, Yasuyuki Furuta, Hannosuke Wakushima, Hajime Fujii, Ken-ichi Saito, Yoshihiro Kano
Anti-allergic effect of Perilla frutescens and its active constituents
Phytotherapy Res. 17 (3): 240-243, 2003
Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Yoshiharu Deguchi, Yoshihiro Kano
Pharmacokinetic and pharmacological interactions between ticlopidine hydrochloride and Kangen-Karyu, a Chinese traditional herbal medicine.
Phytotherapy Res. 17 (9): 1021-1024, 2003
Toshiaki Makino, Seiichi Yamaji
Adverse effects and poisoning about medicinal plants and herbs in Japan (In Japanese)
Japanese Journal of Medicinal Plants 26(1): 30-37, 2003
Toshiaki Makino
Pharmacy and pharmacognosy for 21 century (In Japanese)
Journal of Japanerse Scientists 38(12): 652-657, 2003
Toshiaki Makino
History for the usage of herbal medicine in the United States shown in the successive pharmacopoeia (In Japanese)
Japanese Journal of Social Pharmacy 22(2): 2-14, 2003
2002
Toshiaki Makino, Gisho Honda, Takahiko Ono, Eri Muso
Effect of Perilla frutescens on production of nitric oxide and DNA synthesis of murine cultured vascular smooth muscle cell
Phytother Res. 16 (S1): 19-23, 2002
Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Ken-ichi Saito, Yoshihiro Kano
Effects of Kangen-Karyu on coagulation system and platelet aggregation in mice
Biol. Pharm. Bull. 25 (4): 523-525, 2002
Toshiaki Makino, Hannosuke Wakushima, Takuya Okamoto, Yasuhiro Okukubo, Yoshiharu Deguchi, Yoshihiro Kano
Pharmacokinetic interactions between warfarin and Kangen-Karyu, a Chinese traditional herbal medicine, and their synergistic actions
J. Ethenopharmacol. 82 (1) 35-40, 2002
Takahiko Ono, Ning Liu, Hitoshi Kusano, Fumiaki Nogaki, Toshiaki Makino, Eri Muso, Shigetake Sasayama
Broad antiproliferative effects of benidipine on cultured human mesangial cells in cell-cycle phases.
Am. J. Nephrol. 22 (5-6): 581-586, 2002
Toshiaki Makino, Takahiko Ono, Ning Liu, Tomoko Nakamura, Eri Muso, Gisho Honda
Suppressive effects of rosmarinic acid on mesangial proliferative glomerulonephritis in rats
Nephron 92 (4): 898-904, 2002
Takahiko Ono, Hiroko Wakasugi, Toshiaki Makino, Sakae Ono
Influx of foreign ethnomedicines into Japan - Safety of dirtary supplements and ethnomedicines (In Japanese)
Latest treatment of Kampo medicine 11(1): 67-72, 2002
2001
Toshiaki Makino, Fumiyuki Kiuchi, Michiho Ito, Takahiko Ono, Eri Muso, Gisho Honda
Inhibitory effect of decoction of Perilla frutescens on cultured murine mesangial cells and quantitative analysis of its active constituents
Planta Medica 67 (1): 24-28, 2001
Toshiaki Makino, Tomoko Nakamura, Takahiko Ono, Eri Muso, Gisho Honda
Suppressive effects of Perilla frutescens on mesangioproliferative glomerulonephritis in rats
Biol. Pharm. Bull. 24 (2): 172-175, 2001
Toshiaki Makino, Yasuyuki Furuta, Hajime Fujii, Takashi Nakagawa, Hannosuke Wakushima, Ken-ichi Saito, Yoshihiro Kano
Effect of oral treatment of Perilla frutescens and its constituents on type-I allergy in mice
Biol. Pharm. Bull. 24 (10): 1206-1209, 2001
Before 2000
Toshiaki Makino, Takahiko Ono, Eri Muso, Haruyoshi Yoshida, Gisho Honda, Shigetake Sasayama
Inhibitory effect of rosmarinic acid on the proliferation of cultured murine mesangial cells
Nephrol. Dialysis. Transplant. 15 (8): 1140-1145, 2000
Toshiaki Makino
Problems of the plant origin for herbal medicines - the topics about aristolochic acid (In Japanese)
Methods in Kampo Phamacology 5:50-54, 2000
Toshiaki Makino, Takahiko Ono, Michiho Ito, Eri Muso, Gisho Honda
Effect of Perilla frutescens extract on nitric oxide production by cultured murine mesangial cells
Biol. Pharm. Bull. 22 (5): 476-480, 1999
Toshiaki Makino, Takahiko Ono, Eri Muso, Gisho Honda
Suppressive effects of Perilla frutescens on spontaneous IgA nephropathy in ddY mice
Nephron 83 (1): 40-46, 1999
Sadahiro Kawazoe, Toshiaki Makino, Koji Arizono
Endocrine disruptors and phytoestrogens (In Japanese)
Jap. J. Medicinal Plants 22(1): 24-35, 1999
Toshiaki Makino, Takahiko Ono, Eri Muso, Gisho Honda
Inhibitory effect of Perilla frutescens and its phenolic constituuents on cultured murine mesangial cell proliferation
Planta Medica 64 (6):541-545, 1998
Toshiaki Makino
Nephrotoxic effect of Kampo medicine - topics for so-called Chinese herbs nephropathy (In Japanese)
Jap. J. Medicinal Plants 21 (1): 35-39, 1998