論文・著書

2018年9月現在

2018

・Tagami T, Ando M, Nagata N, Goto E, Yoshimura N, Takeuchi T, Noda T, Ozeki T. Fabrication of naftopidil-loaded tablets using a semi-solid extrusion-type 3D printer, and the characteristics of the printed hydrogel and resulting tablets. J Pharm Sci. Accepted. (2018)

・Takeuchi T, Tagami T, Fukushige K, Ozeki T. Useful properties of siRNA-coated gold nanoparticles as a mini-nanocarrier platform for intraocular administration. Journal of Drug Delivery Science and Technology. (2018) 47:411-416.

・Morikawa Y, Tagami T, Hoshikawa A, Ozeki T. The use of an efficient microfluidic mixing system for generating stabilized polymeric nanoparticles for controlled drug release. Biol Pharm Bull. (2018) 41(6):899-907.

・Tagami T, Nagata N, Hayashi N, Ogawa E, Fukushige K, Sakai N, Ozeki T. Defined drug release from 3D-printed composite tablets consisting of drug-loaded polyvinylalcohol and a water-soluble or water-insoluble polymer filler. Int J Pharm. (2018) 543(1-2): 361-367.

・Hoshikawa A, Nagira M, Tane M, Fukushige K, Tagami T, Ozeki T. Preparation of curcumin-containing α-, β-, and γ-cyclodextrin/polyethylene glycol-conjugated gold multifunctional nanoparticles and their in vitro cytotoxic effects on A549 cells. Biol Pharm Bull. (2018) 41(6):908-914.

・Fuse T, Tagami T, Tane M, Ozeki T. Effective light-triggered contents release from helper lipid-incorporated liposomes co-encapsulating gemcitabine and a water-soluble photosensitizer. Int J Pharm. (2018) 540: 50-56.

・Ibrahim S, Tagami T, Kishi T, Ozeki T. Curcumin marinosomes as promising nano-drug delivery systems for lung cancer. Int J Pharm. (2018) 540: 40-49.

・Wallin M, Tagami T, Chen L, Yang M, Chan HK. Pulmonary drug delivery to older people. Adv Drug Deliv Rev. E-published.

・Noda T, Okuda T, Mizuno R, Ozeki T, Okamoto H. Two-Step Sustained-Release PLGA/Hyaluronic Acid Gel Formulation for Intra-articular Administration.Biol Pharm Bull. (2018) 41(6):937-943.

・Alenezi A, Naito Y, Terukina T, Prananingrum W, Jinno Y, Tagami T, Ozeki T, Galli S, Jimbo R. Controlled release of clarithromycin from PLGA microparticles enhances bone regeneration in rabbit calvaria defects. J Biomed Mater Res Part B (2018) 106(1):201-208.

・田上 辰秋, 尾関 哲也.「スプレードライ法によるナノコンポジット粒子の調製と吸収剤への応用」経肺投与製剤とデバイスの開発. シーエムシー出版 (2018) In press.

・田上 辰秋, 尾関 哲也. 「バイオ医薬品のDDS~生分解性ポリマー・ハイドロゲルを用いたタンパク医薬品の薬物放出制御に関する最近の研究~」バイオ医薬品の開発と市場 2019. シーエムシー出版 (2018) In press.

・田上 辰秋, 尾関 哲也. 「ナノメディシンに関する臨床試験の動向」「ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発」シーエムシー出版 (2018) p21-32

・田上 辰秋, 尾関 哲也. 「取り巻く話題: 製剤分野における3Dプリント技術の活用:3Dプリンター錠剤・医薬品に関する最近の話題」 製剤機械技術会誌 (2018) 27(1):57-62.

・田上 辰秋, 尾関 哲也. 「研究・技術の開発: 熱溶融積層方式3Dプリンターによる新しい製造アプローチとしての錠剤設計」製剤機械技術会誌 (2018) 27(1):51-56.

・田上 辰秋, 尾関 哲也. 「ナノメディシン創薬の教育現場」 ファルマシア. (2018) 54(1):51-53.

2017

・Ibrahim S, Tagami T, Ozeki T. Effective-loading of platinum-chloroquine into PEGylated neutral and cationic liposomes as a drug delivery system for resistant malaria parasites. Biol Pharm Bull. (2017) 40: 815-823.

・Tagami T, Ozeki T. Recent trend of carrier-based drug delivery in clinical trials. J Pharm Sci. (2017) 106(9): 2219-2226.

・Fukushige K, Tagami T, Ozeki T. The offset effect of a hyaluronic acid coating to cationic carriers containing siRNA: Alleviated cytotoxicity and retained gene silencing in vitro. Journal of Drug Delivery Science and Technology. (2017) 39: 435-441.

・Noda T, Okuda T, Ban K, Mizuno R, Tagami T, Ozeki T, Okamoto H. Development of intra-knee joint sustained release gel formulation and evaluation of its pharmacological efficiency in rat. Biol Pharm Bull. (2017) 40(6):830-836.

・Hoshikawa A, Tagami T, Morimura C, Fukushige K, Ozeki T. Ranibizumab biosimilar/ polyethyleneglycol-conjugated gold nanoparticles as a novel drug delivery platform for age-related macular degeneration. Journal of Drug Delivery Science and Technology. (2017) 38:45-50.

・Tagami T, Fukushige K, Ogawa E, Hayashi N, Ozeki T. 3D printing factors important for the fabrication of polyvinylalcohol filament-based tablets. Biol Pharm Bull. (2017) 40(3):357-364.

・Taki M, Tagami T, Ozeki T. Preparation of polymer-blended quinine nanocomposite particles by spray drying and assessment of their instrumental bitterness-masking effect using a taste sensor. Drug Dev Ind Pharm. (2017) 43(5): 715-722.

・Tagami T, Ando Y, Ozeki T. Fabrication of liposomal doxorubicin exhibiting ultrasensitivity against phospholipase A2 for efficient pulmonary drug delivery to lung cancers. Int J Pharm. (2017) 517: 35-41.

・Yoshimura M, Miyake M, Kawato T, Bando M, Toda M, Kato Y, Fukami T, Ozeki T. Impact of the Dissolution Profile of the Cilostazol Cocrystal with Supersaturation on the Oral Bioavailability. Cryst. Growth Des. (2017) 17 (2):550–557.

・Tanetsugu T, Tagami T, Terukina T, Ogawa T, Ohta M, Ozeki T. Development of sustainable release system for ranibizumab biosimilar using poly(lactic-co-glycolic acid) biodegradable polymer based microspheres as a platform. Biol. Pharm. Bull. (2017) 40(2) :145-150.

・田上 辰秋, 尾関 哲也.「第7章 4節 PLGA粒子を用いたDDS技術の開発」最新DDS技術の先端バイオ医薬品への応用開発. 技術情報協会. (2017) 395-400.

・田上 辰秋, 尾関 哲也. 医師と薬剤師が共有すべき薬の新知識/serial 19「ナノ・マイクロ粒子のDDS技術と臨床応用」 Organ Biology. (2017) 24(1):54-60.

・田上 辰秋, 尾関 哲也.「スプレードライ法を用いた固体分散体の調製」「難溶解性薬物」の改善、製剤化技術. Pharm Stage. (2017) 17(8):29-31

2016

・Otsuka M, Maeno Y, Fukami T, Inoue M, Tagami T, Ozeki T. Solid dispersions of efonidipine hydrochloride ethanolate with improved physicochemical and pharmacokinetic properties prepared with microwave treatment. Eur J Pharm Biopharm. (2016) 108: 25-31.

・Taki M, Tagami T, Fukushige K, Ozeki T. Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation. Int J Pharm. (2016) 11(1):104-10.

・Nakane D, Tagami T, Inomata T, Ichikawa Y, Nakada A, Ozeki T, Masuda H. Dissolution of water-insoluble curcumin by femtosecond-laser ablation in the presence of cyclodextrins and its cytotoxic bioactivity against lung cancer cells. Chemistry letters. (2016) 45(9):1072-1074.

・Miyahara S, Tagami T, Wakabayashi R, Miyazaki I, Murata N, Takahashi Y, Ohkubo H, Ozeki T. Manufacturing control of drugs in opaque packages using an X-ray scanning system and assessment of the irradiation effects on the drug qualities. Japan Society of Pharmaceutical Machinery and Engineering. (2016) 25(2):112-118.

・Terukina T, Naito Y, Tagami T, Morikawa, Y, Henmi Y, Pranaingrum W, Ichikawa T, Ozeki T. The effect of the release behavior of simvastatin from different PLGA particles on bone regeneration in vitro and in vivo: comparison of simvastatin-loaded PLGA microparticles and nanospeheres. Journal of Drug Delivery Science and Technology. (2016) 33: 136-142.

・Nishiyama T, Ogata T, Ozeki T. Preparation of bitter taste-masking granules of lafutidine for orally disintegrating tablets using water-insoluble/soluble polymer combinations. Journal of Drug Delivery Science and Technology. (2016) 32: 38-42.

・Tagami T, Taki M, Ozeki T. Nanoparticulate drug delivery systems to overcome the blood-brain barrier. Nanomaterials in Pharmacology. Springer. Invited review (2016) Chapter 17: 333-348.

・田上 辰秋, 尾関 哲也.「剤形の進歩:経肺投与経路を利用したインスリン吸入製剤とDDS技術」Drug Delivery System. (2016) 31(5):432-439.

2015

・Tagami T, Yanai H, Terada Y, Ozeki T. Evaluation of phosphatidylserine-specific peptide-conjugated liposomes using a model system of malaria-infected erythrocytes. Biol. Pharm. Bull. (2015) 38(10):1649-51.

・Tagami T, Kubota M, Ozeki T. Effective Remote Loading of Doxorubicin into DPPC/Poloxamer 188 Hybrid Liposome to Retain Thermosensitive Property and the Assessment of Carrier-Based Acute Cytotoxicity for Pulmonary Administration. J Pharm Sci. (2015) 104(11):3824-32.

・Mizusako H, Tagami T, Hattori K, Ozeki T. Active Drug Targeting of a Folate-Based Cyclodextrin-Doxorubicin Conjugate and the Cytotoxic Effect on Drug-Resistant Mammary Tumor Cells In Vitro. J Pharm Sci. (2015) 104(9):2934-40.

・Uehara K, Tagami T, Miyazaki I, Murata N, Takahashi Y, Ohkubo H, Ozeki T. Effect of X-ray exposure on the pharmaceutical quality of drug tablets using X-ray inspection equipment. Drug Dev Ind Pharm. (2015) 41(6):953-8.

・Otsuka M, Maeno Y, Fukami T, Inoue M, Tagami T, Ozeki T. Developmental considerations for ethanolates with regard to stability and physicochemical characterization of efonidipine hydrochloride ethanolate. CrystEngComm. (2015) 17, 7430-7436.

・田上 辰秋,尾関 哲也.「生体適合性ナノスフェア」DDSキャリア作製プロトコル集. シーエムシー出版 (2015) p205-212.

2014

・Maeno Y, Fukami T, Kawahata M, Yamaguchi K, Tagami T, Ozeki T, Suzuki T, Tomono K. Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former. Int J Pharm. (2014) 473(1-2):179-86.

・Ozeki T, Tagami T. Drug/polymer nanoparticles prepared using unique spray nozzles and recent progress of inhaled formulation. Asian J Pharm Sci. (2014) 9(5):236-43. Review.

・Tagami T, Imao Y, Ito S, Nakada A, Ozeki T. Simple and effective preparation of nano-pulverized curcumin by femtosecond laser ablation and the cytotoxic effect on C6 rat glioma cells in vitro. Int J Pharm. (2014) 468(1-2):91-6.

・Naito Y, Terukina T, Galli S, Kozai Y, Vandeweghe S, Tagami T, Ozeki T, Ichikawa T, Coelho PG, Jimbo R. The effect of simvastatin-loaded polymeric microspheres in a critical size bone defect in the rabbit calvaria. Int J Pharm. (2014) 461(1-2):157-62.

・ 田上 辰秋, 尾関 哲也. 「他分野との融合・連携が生み出す新しい製剤学・ドラッグデリバリーシステム研究」 PHARM TECH JAPAN. 30(11): 135-140 (2014)

・田上 辰秋, 尾関 哲也. 「経肺投与型製剤の動向および2液混合型スプレーノズルによるナノコンポジット粒子製造技術の開発と応用」医薬ジャーナル. 50(9): 67-72 (2014)